Intraerythrocyte Non-Protein-Bound Iron in Children with Bronchopulmonary Pathology

A total of 230 children having bronchopulmonary pathology (BPP) were examined. Patients were divided into 4 groups according to their intraerythrocyte non-protein- bound iron (IE-NPBI) levels. We investigated the relationship of the IE-NPBI level with parameters of respiratory function (RF) tests, t...

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Main Authors: E.M. Vasilyeva, O.F. Lukina, M.I. Bakanov, K.A. Zykov, A.O. Bogatyreva, A.V. Rvacheva, V.S. Reutova, Beilina, T.N. Kuznetzova, J.V. Solovjeva, N.N. Mazanova
Format: Article
Language:English
Published: International Medical Research and Development Corporation 2014-12-01
Series:International Journal of Biomedicine
Subjects:
Online Access:http://ijbm.org/articles/Article4(4)_PP1.pdf
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author E.M. Vasilyeva
O.F. Lukina
M.I. Bakanov
K.A. Zykov
A.O. Bogatyreva
A.V. Rvacheva
V.S. Reutova
Beilina
T.N. Kuznetzova
J.V. Solovjeva
N.N. Mazanova
author_facet E.M. Vasilyeva
O.F. Lukina
M.I. Bakanov
K.A. Zykov
A.O. Bogatyreva
A.V. Rvacheva
V.S. Reutova
Beilina
T.N. Kuznetzova
J.V. Solovjeva
N.N. Mazanova
author_sort E.M. Vasilyeva
collection DOAJ
description A total of 230 children having bronchopulmonary pathology (BPP) were examined. Patients were divided into 4 groups according to their intraerythrocyte non-protein- bound iron (IE-NPBI) levels. We investigated the relationship of the IE-NPBI level with parameters of respiratory function (RF) tests, the severity of comorbidities, and level of other free intracellular ions, such as copper, zinc, and magnesium. The pronounced increase in IE-NPBI level was typical for patients with the connective tissue dysplasia, often accompanied by mitral valve prolapse, osteopenia, and mineral metabolism violation. The severe comorbid diagnoses were typical for patients with reduced levels of IE-NPBI (chronic cor pulmonale, tuberculosis infection). The largest number of comorbidities, aggravating the underlying disease, took place in the group of patients with a significant reduction in IE-NPBI level. A significant increase in IE-NPBI level, as well as a marked reduction of IE-NPBI level, was an unfavorable factor for the underlying disease. We found a correlation between IE-NPBI level and parameters of RF-test in patients with moderate increase in IE-NPBI level.
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spelling doaj.art-05615175b80448d08c5a16454fa29a8b2022-12-21T17:58:25ZengInternational Medical Research and Development CorporationInternational Journal of Biomedicine2158-05102158-05292014-12-0144231236Intraerythrocyte Non-Protein-Bound Iron in Children with Bronchopulmonary PathologyE.M. Vasilyeva 0O.F. Lukina 1M.I. Bakanov 2K.A. Zykov 3A.O. Bogatyreva 4A.V. Rvacheva 5V.S. Reutova6Beilina 7T.N. Kuznetzova 8J.V. Solovjeva 9N.N. Mazanova10Scientific Center for Children’s Health RAMS;Moscow, Russian Federation.Scientific Center for Children’s Health RAMS;Moscow, Russian Federation.Scientific Center for Children’s Health RAMS;Moscow, Russian Federation.Moscow State University of Medicine and Dentistry; Moscow, Russian FederationMoscow State University of Medicine and Dentistry; Moscow, Russian FederationMoscow State University of Medicine and Dentistry; Moscow, Russian FederationScientific Center for Children’s Health RAMS;Moscow, Russian Federation.Moscow State University of Medicine and Dentistry; Moscow, Russian FederationMoscow State University of Medicine and Dentistry; Moscow, Russian FederationScientific Center for Children’s Health RAMS;Moscow, Russian Federation.Scientific Center for Children’s Health RAMS;Moscow, Russian Federation.A total of 230 children having bronchopulmonary pathology (BPP) were examined. Patients were divided into 4 groups according to their intraerythrocyte non-protein- bound iron (IE-NPBI) levels. We investigated the relationship of the IE-NPBI level with parameters of respiratory function (RF) tests, the severity of comorbidities, and level of other free intracellular ions, such as copper, zinc, and magnesium. The pronounced increase in IE-NPBI level was typical for patients with the connective tissue dysplasia, often accompanied by mitral valve prolapse, osteopenia, and mineral metabolism violation. The severe comorbid diagnoses were typical for patients with reduced levels of IE-NPBI (chronic cor pulmonale, tuberculosis infection). The largest number of comorbidities, aggravating the underlying disease, took place in the group of patients with a significant reduction in IE-NPBI level. A significant increase in IE-NPBI level, as well as a marked reduction of IE-NPBI level, was an unfavorable factor for the underlying disease. We found a correlation between IE-NPBI level and parameters of RF-test in patients with moderate increase in IE-NPBI level.http://ijbm.org/articles/Article4(4)_PP1.pdfchildren;bronchopulmonary pathology;intraerythrocyte non-protein- bound iron;respiratory function.
spellingShingle E.M. Vasilyeva
O.F. Lukina
M.I. Bakanov
K.A. Zykov
A.O. Bogatyreva
A.V. Rvacheva
V.S. Reutova
Beilina
T.N. Kuznetzova
J.V. Solovjeva
N.N. Mazanova
Intraerythrocyte Non-Protein-Bound Iron in Children with Bronchopulmonary Pathology
International Journal of Biomedicine
children;
bronchopulmonary pathology;
intraerythrocyte non-protein- bound iron;
respiratory function.
title Intraerythrocyte Non-Protein-Bound Iron in Children with Bronchopulmonary Pathology
title_full Intraerythrocyte Non-Protein-Bound Iron in Children with Bronchopulmonary Pathology
title_fullStr Intraerythrocyte Non-Protein-Bound Iron in Children with Bronchopulmonary Pathology
title_full_unstemmed Intraerythrocyte Non-Protein-Bound Iron in Children with Bronchopulmonary Pathology
title_short Intraerythrocyte Non-Protein-Bound Iron in Children with Bronchopulmonary Pathology
title_sort intraerythrocyte non protein bound iron in children with bronchopulmonary pathology
topic children;
bronchopulmonary pathology;
intraerythrocyte non-protein- bound iron;
respiratory function.
url http://ijbm.org/articles/Article4(4)_PP1.pdf
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