Lower SLC7A2 expression is associated with enhanced multidrug resistance, less immune infiltrates and worse prognosis of NSCLC

Lower SLC7A2 expression is associated with enhanced multidrug resistance, less immune infiltrates and worse prognosis of NSCLC

Abstract Background Solute carrier family 7 member 2 (SLC7A2), a cationic amino acid transporter, is lowly expressed in ovarian and hepatocellular cancers, which is associated with their worse prognosis. However, its roles in the prognosis, drug resistance and immune infiltration in non-small-cell l...

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Bibliographic Details
Main Authors: Shanshan Jiang, Junrong Zou, Jianyu Dong, Huimian Shi, Jie Chen, Yan Li, Xianglong Duan, Wensheng Li
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Cell Communication and Signaling
Subjects:
SLC7A2
Multiple drug resistance
NSCLC
Immune infiltration
AMPK
Online Access:https://doi.org/10.1186/s12964-022-01023-x

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