COVID-19 Prevalence and Survival Outcome in Pediatric Cancer Patients Undergoing Chemotherapy: A Study from Tertiary Cancer Center of North-East India
Background: Pediatric cancer patients are considered one of vulnerable group for Covid-19 infections and its associated complication. We assessed Covid-19 prevalence and implications in pediatric cancer patients of NorthEast India. Methods: Retrospective study was conducted between July 2020 to Jun...
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| Format: | Article |
| Language: | English |
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West Asia Organization for Cancer Prevention
2022-08-01
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| Series: | Asian Pacific Journal of Cancer Care |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjcc/article/view/780 |
| _version_ | 1797342217566683136 |
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| author | Munlima Hazarika Raghavender Reddy T Avdhesh K Rai Partha S Roy Asif Iqbal Suhani Barbhuiyan Nithin Raj Sreya Mallik Satya S Sarangi |
| author_facet | Munlima Hazarika Raghavender Reddy T Avdhesh K Rai Partha S Roy Asif Iqbal Suhani Barbhuiyan Nithin Raj Sreya Mallik Satya S Sarangi |
| author_sort | Munlima Hazarika |
| collection | DOAJ |
| description | Background: Pediatric cancer patients are considered one of vulnerable group for Covid-19 infections and its associated complication. We assessed Covid-19 prevalence and implications in pediatric cancer patients of NorthEast India.
Methods: Retrospective study was conducted between July 2020 to June 2021 at Dr B Borooah Cancer Institute (BBCI), Guwahati, Assam, India. Medical records of the childhood cancer patients were analyzed. All patients who were tested for SARS-CoV-2 were collected. All childhood cancer patients with age group between one to eighteen years were included.
Results: Fifty two out of 701 (7%) cancer patients in children were found to be positive for SARS-CoV2 by RT-PCR testing. Among COVID-19 positive patients, the median age was six years. In COVID-19 positive group, thirty (57.6 %) were suffering from hematological malignancy and twenty two (42.4%) have solid malignancy. In COVID-19 positive group, Among the hematological malignancies; acute lymphoblastic leukemia (ALL) comprises 70% (21), acute myeloid leukemia (AML) 16.66% (5) and lymphoma accounting for 13.33%. Fever, cough and sore throat was presenting symptom in majority of patients. Survival outcome has shown statistically significant association (p=0.0001) between COVID-19 positive and negative pediatric cancer patients. Eight deaths occurred in COVID-19 positive patients but there was only one death in COVID-19 negative patients.
Conclusion: Among COVID-19 positive childhood cancer patients risk of death was significantly higher compared to COVID-19 negative patients and majority of deaths occurred in hematological malignancies receiving intensive chemotherapy. |
| first_indexed | 2024-03-08T10:30:06Z |
| format | Article |
| id | doaj.art-0568f65810274091adda5813412130c6 |
| institution | Directory Open Access Journal |
| issn | 2588-3682 |
| language | English |
| last_indexed | 2024-03-08T10:30:06Z |
| publishDate | 2022-08-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Cancer Care |
| spelling | doaj.art-0568f65810274091adda5813412130c62024-01-27T05:44:35ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Cancer Care2588-36822022-08-017347548010.31557/apjcc.2022.7.3.475-480780COVID-19 Prevalence and Survival Outcome in Pediatric Cancer Patients Undergoing Chemotherapy: A Study from Tertiary Cancer Center of North-East IndiaMunlima Hazarika0Raghavender Reddy T1Avdhesh K Rai2Partha S Roy3Asif Iqbal4Suhani Barbhuiyan5Nithin Raj6Sreya Mallik7Satya S Sarangi8Department of Pediatric and Medical Oncology, Dr B Borooah Cancer Institute, Guwahati-781016, Assam, India.Department of Pediatric and Medical Oncology, Dr B Borooah Cancer Institute, Guwahati-781016, Assam, India.Molecular Virology Laboratory, DBT Centre for Molecular Biology & Cancer Research, Dr B Borooah Cancer Institute, Guwahati-781016, Assam, India.Department of Pediatric and Medical Oncology, Dr B Borooah Cancer Institute, Guwahati-781016, Assam, India.Department of Pediatric and Medical Oncology, Dr B Borooah Cancer Institute, Guwahati-781016, Assam, India.Department of Pediatric and Medical Oncology, Dr B Borooah Cancer Institute, Guwahati-781016, Assam, India.Department of Pediatric and Medical Oncology, Dr B Borooah Cancer Institute, Guwahati-781016, Assam, India.Department of Pediatric and Medical Oncology, Dr B Borooah Cancer Institute, Guwahati-781016, Assam, India.Department of Pediatric and Medical Oncology, Dr B Borooah Cancer Institute, Guwahati-781016, Assam, India.Background: Pediatric cancer patients are considered one of vulnerable group for Covid-19 infections and its associated complication. We assessed Covid-19 prevalence and implications in pediatric cancer patients of NorthEast India. Methods: Retrospective study was conducted between July 2020 to June 2021 at Dr B Borooah Cancer Institute (BBCI), Guwahati, Assam, India. Medical records of the childhood cancer patients were analyzed. All patients who were tested for SARS-CoV-2 were collected. All childhood cancer patients with age group between one to eighteen years were included. Results: Fifty two out of 701 (7%) cancer patients in children were found to be positive for SARS-CoV2 by RT-PCR testing. Among COVID-19 positive patients, the median age was six years. In COVID-19 positive group, thirty (57.6 %) were suffering from hematological malignancy and twenty two (42.4%) have solid malignancy. In COVID-19 positive group, Among the hematological malignancies; acute lymphoblastic leukemia (ALL) comprises 70% (21), acute myeloid leukemia (AML) 16.66% (5) and lymphoma accounting for 13.33%. Fever, cough and sore throat was presenting symptom in majority of patients. Survival outcome has shown statistically significant association (p=0.0001) between COVID-19 positive and negative pediatric cancer patients. Eight deaths occurred in COVID-19 positive patients but there was only one death in COVID-19 negative patients. Conclusion: Among COVID-19 positive childhood cancer patients risk of death was significantly higher compared to COVID-19 negative patients and majority of deaths occurred in hematological malignancies receiving intensive chemotherapy.http://www.waocp.com/journal/index.php/apjcc/article/view/780covid-19, survival, pediatric cancer patients, chemotherapy, north east india |
| spellingShingle | Munlima Hazarika Raghavender Reddy T Avdhesh K Rai Partha S Roy Asif Iqbal Suhani Barbhuiyan Nithin Raj Sreya Mallik Satya S Sarangi COVID-19 Prevalence and Survival Outcome in Pediatric Cancer Patients Undergoing Chemotherapy: A Study from Tertiary Cancer Center of North-East India Asian Pacific Journal of Cancer Care covid-19, survival, pediatric cancer patients, chemotherapy, north east india |
| title | COVID-19 Prevalence and Survival Outcome in Pediatric Cancer Patients Undergoing Chemotherapy: A Study from Tertiary Cancer Center of North-East India |
| title_full | COVID-19 Prevalence and Survival Outcome in Pediatric Cancer Patients Undergoing Chemotherapy: A Study from Tertiary Cancer Center of North-East India |
| title_fullStr | COVID-19 Prevalence and Survival Outcome in Pediatric Cancer Patients Undergoing Chemotherapy: A Study from Tertiary Cancer Center of North-East India |
| title_full_unstemmed | COVID-19 Prevalence and Survival Outcome in Pediatric Cancer Patients Undergoing Chemotherapy: A Study from Tertiary Cancer Center of North-East India |
| title_short | COVID-19 Prevalence and Survival Outcome in Pediatric Cancer Patients Undergoing Chemotherapy: A Study from Tertiary Cancer Center of North-East India |
| title_sort | covid 19 prevalence and survival outcome in pediatric cancer patients undergoing chemotherapy a study from tertiary cancer center of north east india |
| topic | covid-19, survival, pediatric cancer patients, chemotherapy, north east india |
| url | http://www.waocp.com/journal/index.php/apjcc/article/view/780 |
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