Bioprinting and biomaterials for dental alveolar tissue regeneration
Three dimensional (3D) bioprinting is a powerful tool, that was recently applied to tissue engineering. This technique allows the precise deposition of cells encapsulated in supportive bioinks to fabricate complex scaffolds, which are used to repair targeted tissues. Here, we review the recent devel...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.991821/full |
| _version_ | 1797847201387380736 |
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| author | Serge Ostrovidov Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Hojae Bae Gorka Orive Gorka Orive Gorka Orive Toshinori Fujie Toshinori Fujie Xuetao Shi Hirokazu Kaji |
| author_facet | Serge Ostrovidov Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Hojae Bae Gorka Orive Gorka Orive Gorka Orive Toshinori Fujie Toshinori Fujie Xuetao Shi Hirokazu Kaji |
| author_sort | Serge Ostrovidov |
| collection | DOAJ |
| description | Three dimensional (3D) bioprinting is a powerful tool, that was recently applied to tissue engineering. This technique allows the precise deposition of cells encapsulated in supportive bioinks to fabricate complex scaffolds, which are used to repair targeted tissues. Here, we review the recent developments in the application of 3D bioprinting to dental tissue engineering. These tissues, including teeth, periodontal ligament, alveolar bones, and dental pulp, present cell types and mechanical properties with great heterogeneity, which is challenging to reproduce in vitro. After highlighting the different bioprinting methods used in regenerative dentistry, we reviewed the great variety of bioink formulations and their effects on cells, which have been established to support the development of these tissues. We discussed the different advances achieved in the fabrication of each dental tissue to provide an overview of the current state of the methods. We conclude with the remaining challenges and future needs. |
| first_indexed | 2024-04-09T18:07:28Z |
| format | Article |
| id | doaj.art-0569837f43c5483caaec74dda3fda5ba |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-09T18:07:28Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-0569837f43c5483caaec74dda3fda5ba2023-04-14T05:30:28ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852023-04-011110.3389/fbioe.2023.991821991821Bioprinting and biomaterials for dental alveolar tissue regenerationSerge Ostrovidov0Murugan Ramalingam1Murugan Ramalingam2Murugan Ramalingam3Murugan Ramalingam4Murugan Ramalingam5Murugan Ramalingam6Hojae Bae7Gorka Orive8Gorka Orive9Gorka Orive10Toshinori Fujie11Toshinori Fujie12Xuetao Shi13Hirokazu Kaji14Department of Biomechanics, Institute of Biomaterials and Bioengineering (IBB), Tokyo Medical and Dental University (TMDU), Tokyo, JapanInstitute of Tissue Regeneration Engineering, Dankook University, Cheonan, Republic of KoreaDepartment of Nanobiomedical Science, BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, Republic of KoreaSchool of Basic Medical Science, Chengdu University, Chengdu, ChinaMechanobiology Dental Medicine Research Center, Dankook University, Cheonan, Republic of KoreaUCL Eastman-Korea Dental Medicine Innovation Centre, Dankook University, Cheonan, Republic of KoreaDepartment of Metallurgical and Materials Engineering, Faculty of Engineering, Atilim University, Ankara, TürkiyeDepartment of Stem Cell and Regenerative Biotechnology, KU Convergence Science and Technology Institute, Konkuk University, Hwayang-dong, Seoul, Republic of KoreaNanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain0Bioaraba, NanoBioCel Research Group, Vitoria-Gasteiz, Spain1Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain2School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan3Living System Materialogy (LiSM) Reseach Group, International Research Frontiers Initiative (IRFI), Tokyo Institute of Technology, Yokohama, Japan4National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou, Guangdong, ChinaDepartment of Biomechanics, Institute of Biomaterials and Bioengineering (IBB), Tokyo Medical and Dental University (TMDU), Tokyo, JapanThree dimensional (3D) bioprinting is a powerful tool, that was recently applied to tissue engineering. This technique allows the precise deposition of cells encapsulated in supportive bioinks to fabricate complex scaffolds, which are used to repair targeted tissues. Here, we review the recent developments in the application of 3D bioprinting to dental tissue engineering. These tissues, including teeth, periodontal ligament, alveolar bones, and dental pulp, present cell types and mechanical properties with great heterogeneity, which is challenging to reproduce in vitro. After highlighting the different bioprinting methods used in regenerative dentistry, we reviewed the great variety of bioink formulations and their effects on cells, which have been established to support the development of these tissues. We discussed the different advances achieved in the fabrication of each dental tissue to provide an overview of the current state of the methods. We conclude with the remaining challenges and future needs.https://www.frontiersin.org/articles/10.3389/fbioe.2023.991821/fullbioprintingbiomaterialsbioinkdental tissue engineeringdentistry |
| spellingShingle | Serge Ostrovidov Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Murugan Ramalingam Hojae Bae Gorka Orive Gorka Orive Gorka Orive Toshinori Fujie Toshinori Fujie Xuetao Shi Hirokazu Kaji Bioprinting and biomaterials for dental alveolar tissue regeneration Frontiers in Bioengineering and Biotechnology bioprinting biomaterials bioink dental tissue engineering dentistry |
| title | Bioprinting and biomaterials for dental alveolar tissue regeneration |
| title_full | Bioprinting and biomaterials for dental alveolar tissue regeneration |
| title_fullStr | Bioprinting and biomaterials for dental alveolar tissue regeneration |
| title_full_unstemmed | Bioprinting and biomaterials for dental alveolar tissue regeneration |
| title_short | Bioprinting and biomaterials for dental alveolar tissue regeneration |
| title_sort | bioprinting and biomaterials for dental alveolar tissue regeneration |
| topic | bioprinting biomaterials bioink dental tissue engineering dentistry |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2023.991821/full |
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