GM3 Ganglioside Linked to Neurofibrillary Pathology in a Transgenic Rat Model for Tauopathy

GM3 Ganglioside Linked to Neurofibrillary Pathology in a Transgenic Rat Model for Tauopathy

Glycosphingolipids (GSLs) are amphipathic lipids composed of a sphingoid base and a fatty acyl attached to a saccharide moiety. GSLs play an important role in signal transduction, directing proteins within the membrane, cell recognition, and modulation of cell adhesion. Gangliosides and sulfatides b...

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Bibliographic Details
Main Authors: Dominika Olešová, Petra Majerová, Roman Hájek, Juraj Piešťanský, Radana Brumarová, Alena Michalicová, Bernadeta Jurkanin, David Friedecký, Andrej Kováč
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
glycosphingolipids
gangliosides
sulfatides
tauopathy
neurodegeneration
aging
Online Access:https://www.mdpi.com/1422-0067/22/22/12581

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