Chemogenetic regulation of the TARP-lipid interaction mimics LTP and reversibly modifies behavior

Chemogenetic regulation of the TARP-lipid interaction mimics LTP and reversibly modifies behavior

Summary: Long-term potentiation (LTP), a well-characterized form of synaptic plasticity, is believed to underlie memory formation. Hebbian, postsynaptically expressed LTP requires TARPγ-8 phosphorylation for synaptic insertion of AMPA receptors (AMPARs). However, it is unknown whether TARP-mediated...

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Bibliographic Details
Main Authors: Joongkyu Park, Coralie Berthoux, Erika Hoyos-Ramirez, Lili Shan, Megumi Morimoto-Tomita, Yixiang Wang, Pablo E. Castillo, Susumu Tomita
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Neuroscience
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723008379

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