The effects of extreme low frequency pulsed electromagnetic field on bone mineral density and incidence of fractures in patients with end - stage renal disease on dialysis - three year follow up study
Background/Aim. A variety of physical therapy options has been developed for the treatment of musculoskeletal disorders including those characterized with low bone mineral density (BMD). Extreme low frequency pulsed electromagnetic field (ELF-PEMF) can accelerate bone formation. Patients with end st...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2018-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600212R.pdf |
| _version_ | 1811258270643388416 |
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| author | Rakočević-Hrnjak Aleksandra Vuksanović Miljanka Dimković Nada Đurović Aleksandar Petronijević Nataša Petronijević Milan |
| author_facet | Rakočević-Hrnjak Aleksandra Vuksanović Miljanka Dimković Nada Đurović Aleksandar Petronijević Nataša Petronijević Milan |
| author_sort | Rakočević-Hrnjak Aleksandra |
| collection | DOAJ |
| description | Background/Aim. A variety of physical therapy options has been developed for the treatment of musculoskeletal disorders including those characterized with low bone mineral density (BMD). Extreme low frequency pulsed electromagnetic field (ELF-PEMF) can accelerate bone formation. Patients with end stage of renal disease (ESRD) are predisposed to high incidence of fractures due to bone disorder with multifactorial pathogenesis. Vitamin D, calcium supplements, antiresorptive and anabolic drugs in those patients have changed pharmacodynamics and pharmacokinetics and have minimal or limited effects. The aim of this study was to assess the effectiveness of long-term ELF-PEMF therapy applied in concordance with physical exercise on bone mass, incidence of new bone fractures and parathyroid hormone concentrations in ESRD patients on dialysis. Methods. In this 3-year prospective clinical trial, 151 patients with ESRD on dialysis program were subjected to treatment with ELF-PEMF (18 Hz, 2 mT) applied during 40 min after 10 consecutive dialysis procedures, 4 times through one year (120 treatments in total during three years) together with kinesitherapy (study group) or only with kinesitherapy (control group) on the voluntary basis. Results. Total of 124 patients have completed the study. In the study group (n = 54), regardless of sex, significant improvements of BMD, T-score and Z-score on both lumbar spine and femoral neck were achieved after 3-year treatment with ELF-PEMF. In the control group (n = 70), significant decreases of BMD, T-score and Z-score as well as the higher incidence of new bone fractures were recorded. Conclusion. ELF-PEMF could be a convenient and safe non-pharmacological therapeutic strategy for fracture prevention in nephrology practices. |
| first_indexed | 2024-04-12T18:10:43Z |
| format | Article |
| id | doaj.art-056e4509ac734bdca650dac44fda225d |
| institution | Directory Open Access Journal |
| issn | 0042-8450 2406-0720 |
| language | English |
| last_indexed | 2024-04-12T18:10:43Z |
| publishDate | 2018-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-056e4509ac734bdca650dac44fda225d2022-12-22T03:21:50ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202018-01-0175327328010.2298/VSP160617212R0042-84501600212RThe effects of extreme low frequency pulsed electromagnetic field on bone mineral density and incidence of fractures in patients with end - stage renal disease on dialysis - three year follow up studyRakočević-Hrnjak Aleksandra0Vuksanović Miljanka1Dimković Nada2Đurović Aleksandar3Petronijević Nataša4https://orcid.org/0000-0002-4338-1953Petronijević Milan5https://orcid.org/0000-0001-5774-3858University Medical Centre Zvezdara, Centre of Physical Medicine and Rehabilitation, BelgradeUniversity Medical Centre Zvezdara, Clinic of Internal Medicine, BelgradeUniversity Medical Centre Zvezdara, Clinic of Internal Medicine, BelgradeUniversity of Defence, Military Medical Academy, Medical Faculty, Clinic for Physical Medicine and Rehabilitation, BelgradeSchool of Medicine, Institute of Medical and Clinical Biochemistry, BelgradeUniversity of Defence, Military Medical Academy, Medical Faculty, Clinic for Rheumatology and Clinical Immunology, BelgradeBackground/Aim. A variety of physical therapy options has been developed for the treatment of musculoskeletal disorders including those characterized with low bone mineral density (BMD). Extreme low frequency pulsed electromagnetic field (ELF-PEMF) can accelerate bone formation. Patients with end stage of renal disease (ESRD) are predisposed to high incidence of fractures due to bone disorder with multifactorial pathogenesis. Vitamin D, calcium supplements, antiresorptive and anabolic drugs in those patients have changed pharmacodynamics and pharmacokinetics and have minimal or limited effects. The aim of this study was to assess the effectiveness of long-term ELF-PEMF therapy applied in concordance with physical exercise on bone mass, incidence of new bone fractures and parathyroid hormone concentrations in ESRD patients on dialysis. Methods. In this 3-year prospective clinical trial, 151 patients with ESRD on dialysis program were subjected to treatment with ELF-PEMF (18 Hz, 2 mT) applied during 40 min after 10 consecutive dialysis procedures, 4 times through one year (120 treatments in total during three years) together with kinesitherapy (study group) or only with kinesitherapy (control group) on the voluntary basis. Results. Total of 124 patients have completed the study. In the study group (n = 54), regardless of sex, significant improvements of BMD, T-score and Z-score on both lumbar spine and femoral neck were achieved after 3-year treatment with ELF-PEMF. In the control group (n = 70), significant decreases of BMD, T-score and Z-score as well as the higher incidence of new bone fractures were recorded. Conclusion. ELF-PEMF could be a convenient and safe non-pharmacological therapeutic strategy for fracture prevention in nephrology practices.http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600212R.pdfkidney failure, chronicrenal dialysiselectromagnetic fieldsbone densityfractures, bonesincidencetreatment outcome |
| spellingShingle | Rakočević-Hrnjak Aleksandra Vuksanović Miljanka Dimković Nada Đurović Aleksandar Petronijević Nataša Petronijević Milan The effects of extreme low frequency pulsed electromagnetic field on bone mineral density and incidence of fractures in patients with end - stage renal disease on dialysis - three year follow up study Vojnosanitetski Pregled kidney failure, chronic renal dialysis electromagnetic fields bone density fractures, bones incidence treatment outcome |
| title | The effects of extreme low frequency pulsed electromagnetic field on bone mineral density and incidence of fractures in patients with end - stage renal disease on dialysis - three year follow up study |
| title_full | The effects of extreme low frequency pulsed electromagnetic field on bone mineral density and incidence of fractures in patients with end - stage renal disease on dialysis - three year follow up study |
| title_fullStr | The effects of extreme low frequency pulsed electromagnetic field on bone mineral density and incidence of fractures in patients with end - stage renal disease on dialysis - three year follow up study |
| title_full_unstemmed | The effects of extreme low frequency pulsed electromagnetic field on bone mineral density and incidence of fractures in patients with end - stage renal disease on dialysis - three year follow up study |
| title_short | The effects of extreme low frequency pulsed electromagnetic field on bone mineral density and incidence of fractures in patients with end - stage renal disease on dialysis - three year follow up study |
| title_sort | effects of extreme low frequency pulsed electromagnetic field on bone mineral density and incidence of fractures in patients with end stage renal disease on dialysis three year follow up study |
| topic | kidney failure, chronic renal dialysis electromagnetic fields bone density fractures, bones incidence treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600212R.pdf |
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