The Small Molecule GAL-201 Efficiently Detoxifies Soluble Amyloid β Oligomers: New Approach towards Oral Disease-Modifying Treatment of Alzheimer’s Disease
Soluble amyloid β (Aβ) oligomers have been shown to be highly toxic to neurons and are considered to be a major cause of the neurodegeneration underlying Alzheimer’s disease (AD). That makes soluble Aβ oligomers a promising drug target. In addition to eliminating these toxic species from the patient...
Main Authors: | Hermann Russ, Michele Mazzanti, Chris Parsons, Katrin Riemann, Alexander Gebauer, Gerhard Rammes |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-05-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/10/5794 |
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