Hyaluronic Acid-Glycine-Cholesterol Conjugate-Based Nanoemulsion as a Potent Vaccine Adjuvant for T Cell-Mediated Immunity

Hyaluronic Acid-Glycine-Cholesterol Conjugate-Based Nanoemulsion as a Potent Vaccine Adjuvant for T Cell-Mediated Immunity

Clinical cases of allergic reaction that are due to excipients containing polyethylene glycol (PEG), a hydrophilic molecule commonly used in drug/vaccine formulations, has attracted much attention in recent years. In order to develop PEG-free adjuvants, we investigated the feasibility of natural ing...

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Bibliographic Details
Main Authors: Chih-An Lin, Hui-Min Ho, Parthiban Venkatesan, Chiung-Yi Huang, Yu-Jhen Cheng, Yu-Hsing Lin, Hua-Yang Lin, Tzu-Yang Chen, Ming-Hsi Huang, Ping-Shan Lai
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
hyaluronic acid
cholesterol
squalene
nanoemulsion
vaccine adjuvants
PEG-free formulation
Online Access:https://www.mdpi.com/1999-4923/13/10/1569

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