Ginkgo biloba extract (EGb761) inhibits autophagy and apoptosis in a rat model of vascular dementia via the AMPK-mTOR signalling pathway

Ginkgo biloba extract (EGb761) inhibits autophagy and apoptosis in a rat model of vascular dementia via the AMPK-mTOR signalling pathway

Vascular dementia (VD), a chronic syndrome of acquired intellectual impairment resulting from cerebrovascular diseases, is closely linked to neuronal autophagy and apoptosis. As a standardized extract from Ginkgo biloba L. leaves, EGb761 is widely applied for treating cerebrovascular diseases owing...

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Bibliographic Details
Main Authors: Yue Yin, Chunyan Yan, Rui Zhang, Yuliang Wang, Yang Song, Shujuan Hu, Xin Zhao, Ruofan Liu, Minghao Guo, Yaxuan Wang, Xin Cai, Dexiu Wang
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Journal of Functional Foods
Subjects:
Ginkgo biloba extract (EGb761)
Vascular dementia
Autophagy
Apoptosis
AMPK-mTOR pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624001701

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