SGK1 in Cancer: Biomarker and Drug Target

SGK1 in Cancer: Biomarker and Drug Target

Serum- and glucocorticoid-regulated kinases (SGKs) are members of the AGC family of serine/threonine kinases, consisting of three isoforms: SGK1, SGK2, and SGK3. SGK1 was initially cloned as a gene transcriptionally stimulated by serum and glucocorticoids in rat mammary tumor cells. It is upregulate...

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Bibliographic Details
Main Authors: Jonas Cicenas, Edita Meskinyte-Kausiliene, Vigilijus Jukna, Arnas Rimkus, Jokubas Simkus, Diana Soderholm
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
SGK1
SGK1 inhibitors
cancer
phosphorylation
biomarkers
kinases
Online Access:https://www.mdpi.com/2072-6694/14/10/2385

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