Recent Advances in Quaternary Ammonium Monomers for Dental Applications
Resin-based dental materials have been one of the ideal choices among various materials in the treatment of dental caries. However, resin-based dental materials still have some drawbacks, such as the lack of inherent antibacterial activity. Extensive research has been conducted on the use of novel q...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/17/2/345 |
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| author | Xiaoxu Liang Biao Yu Liuqi Ye Danlei Lin Wen Zhang Hai-Jing Zhong Jingwei He |
| author_facet | Xiaoxu Liang Biao Yu Liuqi Ye Danlei Lin Wen Zhang Hai-Jing Zhong Jingwei He |
| author_sort | Xiaoxu Liang |
| collection | DOAJ |
| description | Resin-based dental materials have been one of the ideal choices among various materials in the treatment of dental caries. However, resin-based dental materials still have some drawbacks, such as the lack of inherent antibacterial activity. Extensive research has been conducted on the use of novel quaternary ammonium monomers (QAMs) to impart antibacterial activity to dental materials. This review provides a comprehensive overview of the recent advances in quaternary ammonium monomers (QAMs) for dental applications. The current progress and limitations of QAMs are discussed based on the evolution of their structures. The functional diversification and enhancement of QAMs are presented. QAMs have the potential to provide long-term antibacterial activity in dental resin composites, thereby prolonging their service life. However, there is a need to balance antibacterial performance with other material properties and the potential impact on the oral microbiome and general health. Finally, the necessity for further scientific progress in the development of novel quaternary ammonium monomers and the optimization of dental resin formulations is emphasized. |
| first_indexed | 2024-03-08T10:42:53Z |
| format | Article |
| id | doaj.art-057c063e14bc4572b46a7d69fc190c2a |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-08T10:42:53Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-057c063e14bc4572b46a7d69fc190c2a2024-01-26T17:26:49ZengMDPI AGMaterials1996-19442024-01-0117234510.3390/ma17020345Recent Advances in Quaternary Ammonium Monomers for Dental ApplicationsXiaoxu Liang0Biao Yu1Liuqi Ye2Danlei Lin3Wen Zhang4Hai-Jing Zhong5Jingwei He6Foundation Department, Guangzhou Maritime University, Guangzhou 510725, ChinaSchool of Chemistry and Chemical Engineering, Lingnan Normal University, Zhanjiang 524048, ChinaInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), College of Pharmacy, Jinan University, Guangzhou 510632, ChinaInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), College of Pharmacy, Jinan University, Guangzhou 510632, ChinaInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), College of Pharmacy, Jinan University, Guangzhou 510632, ChinaInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), College of Pharmacy, Jinan University, Guangzhou 510632, ChinaSchool of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, ChinaResin-based dental materials have been one of the ideal choices among various materials in the treatment of dental caries. However, resin-based dental materials still have some drawbacks, such as the lack of inherent antibacterial activity. Extensive research has been conducted on the use of novel quaternary ammonium monomers (QAMs) to impart antibacterial activity to dental materials. This review provides a comprehensive overview of the recent advances in quaternary ammonium monomers (QAMs) for dental applications. The current progress and limitations of QAMs are discussed based on the evolution of their structures. The functional diversification and enhancement of QAMs are presented. QAMs have the potential to provide long-term antibacterial activity in dental resin composites, thereby prolonging their service life. However, there is a need to balance antibacterial performance with other material properties and the potential impact on the oral microbiome and general health. Finally, the necessity for further scientific progress in the development of novel quaternary ammonium monomers and the optimization of dental resin formulations is emphasized.https://www.mdpi.com/1996-1944/17/2/345quaternary ammonium monomersdental materialsantibacterial activitydental caries |
| spellingShingle | Xiaoxu Liang Biao Yu Liuqi Ye Danlei Lin Wen Zhang Hai-Jing Zhong Jingwei He Recent Advances in Quaternary Ammonium Monomers for Dental Applications Materials quaternary ammonium monomers dental materials antibacterial activity dental caries |
| title | Recent Advances in Quaternary Ammonium Monomers for Dental Applications |
| title_full | Recent Advances in Quaternary Ammonium Monomers for Dental Applications |
| title_fullStr | Recent Advances in Quaternary Ammonium Monomers for Dental Applications |
| title_full_unstemmed | Recent Advances in Quaternary Ammonium Monomers for Dental Applications |
| title_short | Recent Advances in Quaternary Ammonium Monomers for Dental Applications |
| title_sort | recent advances in quaternary ammonium monomers for dental applications |
| topic | quaternary ammonium monomers dental materials antibacterial activity dental caries |
| url | https://www.mdpi.com/1996-1944/17/2/345 |
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