Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-Analysis

Background: There is limited data about the short-term stroke mortality rates for patients in treatment settings. Objectives: This study aimed to estimate the short-term stroke (in hospital, one month, one year) mortality rates in Iran through a systematic review and meta-analysis. Materials & M...

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Main Authors: Hossein-Ali Nikbakht, Layla Shojaie, Nasim Niknejad, Soheil Hassanipour, Hassan Soleimanpour, Sohrab Heidari, Sima Afrashteh, Ehsan Sarbazi, Saber Ghaffari-fam
Format: Article
Language:English
Published: Guilan University of Medical Sciences 2022-09-01
Series:Caspian Journal of Neurological Sciences
Subjects:
Online Access:http://cjns.gums.ac.ir/article-1-568-en.html
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author Hossein-Ali Nikbakht
Layla Shojaie
Nasim Niknejad
Soheil Hassanipour
Hassan Soleimanpour
Sohrab Heidari
Sima Afrashteh
Ehsan Sarbazi
Saber Ghaffari-fam
author_facet Hossein-Ali Nikbakht
Layla Shojaie
Nasim Niknejad
Soheil Hassanipour
Hassan Soleimanpour
Sohrab Heidari
Sima Afrashteh
Ehsan Sarbazi
Saber Ghaffari-fam
author_sort Hossein-Ali Nikbakht
collection DOAJ
description Background: There is limited data about the short-term stroke mortality rates for patients in treatment settings. Objectives: This study aimed to estimate the short-term stroke (in hospital, one month, one year) mortality rates in Iran through a systematic review and meta-analysis. Materials & Methods: We searched electronic databases, including three national (IranDoc, Megiran, SID) and four international (Scopus, PubMed, Web of Science, Google Scholar), from January 1990 to March 2020. We considered all observational studies on stroke mortality, such as cohort and crosssectional studies. Furthermore, the sub-group analyses were performed based on each province and metaregression analysis based on the study’s year and patients’ mean age. Results: Among 143 studies, 28 were eligible (11 cohort and 17 cross-sectional studies). Based on the random model, the mortality rates for in-hospital, 1-month, and 1-year mortality were reported as 18.71% (95% CI: 15.09%-22.34%), 23.43% (95% CI: 20.08%-26.78%), and 34.44% (95% CI: 32.02%- 36.85%), respectively. The results also revealed that mortality rates were neither related to the year studies conducted nor to the patient’s age. Conclusion: Approximately one-fifth of stroke patients in Iran die in the hospital after admission. The mortality rate increased in the one-month and one-year period, and about one-third of the patients died in the first year. Therefore, it is cardinal to focus on programs and solutions in which we can ameliorate mortality in the short-term period after stroke by performing primary specific treatments on patients.
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spelling doaj.art-05802577dc624e679234a8a4d438ebf62022-12-22T02:37:19ZengGuilan University of Medical SciencesCaspian Journal of Neurological Sciences2423-48182022-09-0184252267Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-AnalysisHossein-Ali Nikbakht0Layla Shojaie1Nasim Niknejad2Soheil Hassanipour3Hassan Soleimanpour4Sohrab Heidari5Sima Afrashteh6Ehsan Sarbazi7Saber Ghaffari-fam8 Social Determinants of Health Research Center of Babol University of Medical Sciences, Babol University of Medical Sciences, Babol, Iran Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, United States Department of Population and Public Health, School of Population and Public Health, The University of British Columbia, Vancouver, Canada Department of Cardiology, Cardiovascular Diseases Research Center, School of Medicine, Heshmat Hospital, Guilan University of Medical Sciences, Rasht, Iran Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran Nursing School of Miyandoab, Urmia University of Medical Sciences, Urmia, Iran Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran Student Research Committee, Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Nursing School of Miyandoab, Urmia University of Medical Sciences, Urmia, Iran Background: There is limited data about the short-term stroke mortality rates for patients in treatment settings. Objectives: This study aimed to estimate the short-term stroke (in hospital, one month, one year) mortality rates in Iran through a systematic review and meta-analysis. Materials & Methods: We searched electronic databases, including three national (IranDoc, Megiran, SID) and four international (Scopus, PubMed, Web of Science, Google Scholar), from January 1990 to March 2020. We considered all observational studies on stroke mortality, such as cohort and crosssectional studies. Furthermore, the sub-group analyses were performed based on each province and metaregression analysis based on the study’s year and patients’ mean age. Results: Among 143 studies, 28 were eligible (11 cohort and 17 cross-sectional studies). Based on the random model, the mortality rates for in-hospital, 1-month, and 1-year mortality were reported as 18.71% (95% CI: 15.09%-22.34%), 23.43% (95% CI: 20.08%-26.78%), and 34.44% (95% CI: 32.02%- 36.85%), respectively. The results also revealed that mortality rates were neither related to the year studies conducted nor to the patient’s age. Conclusion: Approximately one-fifth of stroke patients in Iran die in the hospital after admission. The mortality rate increased in the one-month and one-year period, and about one-third of the patients died in the first year. Therefore, it is cardinal to focus on programs and solutions in which we can ameliorate mortality in the short-term period after stroke by performing primary specific treatments on patients.http://cjns.gums.ac.ir/article-1-568-en.htmlstrokemortalitysystematic reviewmeta-analysisiran
spellingShingle Hossein-Ali Nikbakht
Layla Shojaie
Nasim Niknejad
Soheil Hassanipour
Hassan Soleimanpour
Sohrab Heidari
Sima Afrashteh
Ehsan Sarbazi
Saber Ghaffari-fam
Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-Analysis
Caspian Journal of Neurological Sciences
stroke
mortality
systematic review
meta-analysis
iran
title Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-Analysis
title_full Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-Analysis
title_fullStr Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-Analysis
title_full_unstemmed Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-Analysis
title_short Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-Analysis
title_sort mortality rate of acute stroke in iran a systematic review and meta analysis
topic stroke
mortality
systematic review
meta-analysis
iran
url http://cjns.gums.ac.ir/article-1-568-en.html
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