Conjunctival bacterial infection among hospitalized neonates
Background: Conjunctivitis is a common infection among neonates and it is a known cause of preventable childhood blindness. There is geographical variation in the distribution of aetiological agents. Objective: To assess the prevalence of conjunctivitis among hospitalized neonates receiving care...
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| Format: | Article |
| Language: | English |
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Medical and Dental Consultants Association of Nigeria, OOUTH Sagamu
2020-05-01
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| Series: | Annals of Health Research |
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| Online Access: | https://www.annalsofhealthresearch.com/index.php/ahr/article/view/275 |
| _version_ | 1818144550119538688 |
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| author | OB Ogunfowora JO Ajewole HA Ajibode |
| author_facet | OB Ogunfowora JO Ajewole HA Ajibode |
| author_sort | OB Ogunfowora |
| collection | DOAJ |
| description | Background: Conjunctivitis is a common infection among neonates and it is a known cause of preventable childhood blindness. There is geographical variation in the distribution of aetiological agents.
Objective: To assess the prevalence of conjunctivitis among hospitalized neonates receiving care in a tertiary health care centre in South-west Nigeria, and describe its clinical and bacteriological correlates.
Methods: The hospital records of neonates diagnosed with conjunctivitis at the Olabisi Onabanjo University Teaching Hospital, Sagamu between January 2015 and December 2019 were reviewed. Their bio-data, perinatal history, laboratory results and treatment received were extracted for analysis.
Results: One hundred and twenty-two neonates had conjunctivitis out of a total number of 2,286 admissions, giving a prevalence rate of 5.3%. Male infants had almost double the risk of developing the disease compared to female infants (OR = 1.6; 95% CI: 1.09-2.35). Eighty-six (70.5%) babies were term, while 21 (17.2%) and 15 (12.3%) were preterm and small-for-gestational-age respectively. Most cases of neonatal conjunctivitis (82.0%) occurred in the first week of life while the mean ±SD age of onset was 5.3±4.5 days. Staphylococcus aureus and Klebsiella species were the commonest bacterial isolates affecting 57.1% and 23.0% neonates respectively. Moderately-high rates of resistance to erythromycin and gentamicin were observed among the bacterial isolates.
Conclusion: Neonatal conjunctivitis is commonly due to Staphylococcus aureus and Klebsiella species in this setting. It is commoner among male infants. Most cases run a mild course with good response to topical antimicrobial therapy. |
| first_indexed | 2024-12-11T11:49:20Z |
| format | Article |
| id | doaj.art-05842a2bd0924ca1983b248640a89010 |
| institution | Directory Open Access Journal |
| issn | 2476-8642 2536-6149 |
| language | English |
| last_indexed | 2024-12-11T11:49:20Z |
| publishDate | 2020-05-01 |
| publisher | Medical and Dental Consultants Association of Nigeria, OOUTH Sagamu |
| record_format | Article |
| series | Annals of Health Research |
| spelling | doaj.art-05842a2bd0924ca1983b248640a890102022-12-22T01:08:23ZengMedical and Dental Consultants Association of Nigeria, OOUTH SagamuAnnals of Health Research2476-86422536-61492020-05-016223023810.30442/ahr.0602-12-85Conjunctival bacterial infection among hospitalized neonatesOB OgunfoworaJO AjewoleHA AjibodeBackground: Conjunctivitis is a common infection among neonates and it is a known cause of preventable childhood blindness. There is geographical variation in the distribution of aetiological agents. Objective: To assess the prevalence of conjunctivitis among hospitalized neonates receiving care in a tertiary health care centre in South-west Nigeria, and describe its clinical and bacteriological correlates. Methods: The hospital records of neonates diagnosed with conjunctivitis at the Olabisi Onabanjo University Teaching Hospital, Sagamu between January 2015 and December 2019 were reviewed. Their bio-data, perinatal history, laboratory results and treatment received were extracted for analysis. Results: One hundred and twenty-two neonates had conjunctivitis out of a total number of 2,286 admissions, giving a prevalence rate of 5.3%. Male infants had almost double the risk of developing the disease compared to female infants (OR = 1.6; 95% CI: 1.09-2.35). Eighty-six (70.5%) babies were term, while 21 (17.2%) and 15 (12.3%) were preterm and small-for-gestational-age respectively. Most cases of neonatal conjunctivitis (82.0%) occurred in the first week of life while the mean ±SD age of onset was 5.3±4.5 days. Staphylococcus aureus and Klebsiella species were the commonest bacterial isolates affecting 57.1% and 23.0% neonates respectively. Moderately-high rates of resistance to erythromycin and gentamicin were observed among the bacterial isolates. Conclusion: Neonatal conjunctivitis is commonly due to Staphylococcus aureus and Klebsiella species in this setting. It is commoner among male infants. Most cases run a mild course with good response to topical antimicrobial therapy.https://www.annalsofhealthresearch.com/index.php/ahr/article/view/275conjunctivitiseye dischargeneonatesophthalmia neonatorum |
| spellingShingle | OB Ogunfowora JO Ajewole HA Ajibode Conjunctival bacterial infection among hospitalized neonates Annals of Health Research conjunctivitis eye discharge neonates ophthalmia neonatorum |
| title | Conjunctival bacterial infection among hospitalized neonates |
| title_full | Conjunctival bacterial infection among hospitalized neonates |
| title_fullStr | Conjunctival bacterial infection among hospitalized neonates |
| title_full_unstemmed | Conjunctival bacterial infection among hospitalized neonates |
| title_short | Conjunctival bacterial infection among hospitalized neonates |
| title_sort | conjunctival bacterial infection among hospitalized neonates |
| topic | conjunctivitis eye discharge neonates ophthalmia neonatorum |
| url | https://www.annalsofhealthresearch.com/index.php/ahr/article/view/275 |
| work_keys_str_mv | AT obogunfowora conjunctivalbacterialinfectionamonghospitalizedneonates AT joajewole conjunctivalbacterialinfectionamonghospitalizedneonates AT haajibode conjunctivalbacterialinfectionamonghospitalizedneonates |