Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review

Recent developments in optical biosensors based on integrated photonic devices are reviewed with a special emphasis on silicon-on-insulator ring resonators. The review is mainly devoted to the following aspects: (1) Principles of sensing mechanism, (2) sensor design, (3) biofunctionalization procedu...

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Main Authors: Patrick Steglich, Marcel Hülsemann, Birgit Dietzel, Andreas Mai
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/3/519
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author Patrick Steglich
Marcel Hülsemann
Birgit Dietzel
Andreas Mai
author_facet Patrick Steglich
Marcel Hülsemann
Birgit Dietzel
Andreas Mai
author_sort Patrick Steglich
collection DOAJ
description Recent developments in optical biosensors based on integrated photonic devices are reviewed with a special emphasis on silicon-on-insulator ring resonators. The review is mainly devoted to the following aspects: (1) Principles of sensing mechanism, (2) sensor design, (3) biofunctionalization procedures for specific molecule detection and (4) system integration and measurement set-ups. The inherent challenges of implementing photonics-based biosensors to meet specific requirements of applications in medicine, food analysis, and environmental monitoring are discussed.
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spelling doaj.art-058b377ecba24a048fe146f96e0d393b2022-12-22T01:18:48ZengMDPI AGMolecules1420-30492019-01-0124351910.3390/molecules24030519molecules24030519Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A ReviewPatrick Steglich0Marcel Hülsemann1Birgit Dietzel2Andreas Mai3IHP—Leibniz-Institut für Innovative Mikroelektronik, Im Technologiepark 25, 15236 Frankfurt (Oder), GermanyFirst Sensor AG, Peter-Behrens-Straße 15, 12459 Berlin, GermanyTechnische Hochschule Wildau, Hochschulring 1, 15745 Wildau, GermanyIHP—Leibniz-Institut für Innovative Mikroelektronik, Im Technologiepark 25, 15236 Frankfurt (Oder), GermanyRecent developments in optical biosensors based on integrated photonic devices are reviewed with a special emphasis on silicon-on-insulator ring resonators. The review is mainly devoted to the following aspects: (1) Principles of sensing mechanism, (2) sensor design, (3) biofunctionalization procedures for specific molecule detection and (4) system integration and measurement set-ups. The inherent challenges of implementing photonics-based biosensors to meet specific requirements of applications in medicine, food analysis, and environmental monitoring are discussed.https://www.mdpi.com/1420-3049/24/3/519biosensorsbiophotonicsintegrated optical sensorsaptamersbiomaterialsoptical sensorsilicon photonicsring resonatorslab-on-a-chip
spellingShingle Patrick Steglich
Marcel Hülsemann
Birgit Dietzel
Andreas Mai
Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review
Molecules
biosensors
biophotonics
integrated optical sensors
aptamers
biomaterials
optical sensor
silicon photonics
ring resonators
lab-on-a-chip
title Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review
title_full Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review
title_fullStr Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review
title_full_unstemmed Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review
title_short Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review
title_sort optical biosensors based on silicon on insulator ring resonators a review
topic biosensors
biophotonics
integrated optical sensors
aptamers
biomaterials
optical sensor
silicon photonics
ring resonators
lab-on-a-chip
url https://www.mdpi.com/1420-3049/24/3/519
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AT marcelhulsemann opticalbiosensorsbasedonsilicononinsulatorringresonatorsareview
AT birgitdietzel opticalbiosensorsbasedonsilicononinsulatorringresonatorsareview
AT andreasmai opticalbiosensorsbasedonsilicononinsulatorringresonatorsareview