Advances in screening and diagnostic lab-on-chip tools for gynaecological cancers – a review
AbstractGynaecological cancers are a major global health concern due to the lack of effective screening programmes for ovarian and endometrial cancer, for example, and variable access to vaccination and screening tests for cervical cancer in many countries. Recent research on portable and cost-effec...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Artificial Cells, Nanomedicine, and Biotechnology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21691401.2023.2274047 |
| _version_ | 1797631164339453952 |
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| author | Sadeka Nujhat Hannah S. Leese Mirella Di Lorenzo Rebecca Bowen Sandhya Moise |
| author_facet | Sadeka Nujhat Hannah S. Leese Mirella Di Lorenzo Rebecca Bowen Sandhya Moise |
| author_sort | Sadeka Nujhat |
| collection | DOAJ |
| description | AbstractGynaecological cancers are a major global health concern due to the lack of effective screening programmes for ovarian and endometrial cancer, for example, and variable access to vaccination and screening tests for cervical cancer in many countries. Recent research on portable and cost-effective lab-on-a-chip (LoC) technologies show promise for mass screening and diagnostic procedures for gynaecological cancers. However, most LoCs for gynaecological cancer are still in development, with a need to establish and clinically validate factors such as the type of biomarker, sample and method of detection, before patient use. Multiplex approaches, detecting a panel of gynaecological biomarkers in a single LoC, offer potential for more reliable diagnosis. This review highlights the current research on LoCs for gynaecological cancer screening and diagnosis, emphasizing the need for further research and validation prior to their widespread adoption in clinical practice. |
| first_indexed | 2024-03-11T11:18:04Z |
| format | Article |
| id | doaj.art-058e7bf68a1648fb968de25df78c1ed6 |
| institution | Directory Open Access Journal |
| issn | 2169-1401 2169-141X |
| language | English |
| last_indexed | 2024-03-11T11:18:04Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Artificial Cells, Nanomedicine, and Biotechnology |
| spelling | doaj.art-058e7bf68a1648fb968de25df78c1ed62023-11-10T17:19:32ZengTaylor & Francis GroupArtificial Cells, Nanomedicine, and Biotechnology2169-14012169-141X2023-12-0151161862910.1080/21691401.2023.2274047Advances in screening and diagnostic lab-on-chip tools for gynaecological cancers – a reviewSadeka Nujhat0Hannah S. Leese1Mirella Di Lorenzo2Rebecca Bowen3Sandhya Moise4Department of Chemical Engineering, University of Bath, Bath, UKDepartment of Chemical Engineering, University of Bath, Bath, UKDepartment of Chemical Engineering, University of Bath, Bath, UKRoyal United Hospitals Bath NHS Foundation Trust, Bath, UKDepartment of Chemical Engineering, University of Bath, Bath, UKAbstractGynaecological cancers are a major global health concern due to the lack of effective screening programmes for ovarian and endometrial cancer, for example, and variable access to vaccination and screening tests for cervical cancer in many countries. Recent research on portable and cost-effective lab-on-a-chip (LoC) technologies show promise for mass screening and diagnostic procedures for gynaecological cancers. However, most LoCs for gynaecological cancer are still in development, with a need to establish and clinically validate factors such as the type of biomarker, sample and method of detection, before patient use. Multiplex approaches, detecting a panel of gynaecological biomarkers in a single LoC, offer potential for more reliable diagnosis. This review highlights the current research on LoCs for gynaecological cancer screening and diagnosis, emphasizing the need for further research and validation prior to their widespread adoption in clinical practice.https://www.tandfonline.com/doi/10.1080/21691401.2023.2274047Gynaecological cancerslab-on-a-chip (LoC)cancer screeningcancer diagnosismicrofluidics |
| spellingShingle | Sadeka Nujhat Hannah S. Leese Mirella Di Lorenzo Rebecca Bowen Sandhya Moise Advances in screening and diagnostic lab-on-chip tools for gynaecological cancers – a review Artificial Cells, Nanomedicine, and Biotechnology Gynaecological cancers lab-on-a-chip (LoC) cancer screening cancer diagnosis microfluidics |
| title | Advances in screening and diagnostic lab-on-chip tools for gynaecological cancers – a review |
| title_full | Advances in screening and diagnostic lab-on-chip tools for gynaecological cancers – a review |
| title_fullStr | Advances in screening and diagnostic lab-on-chip tools for gynaecological cancers – a review |
| title_full_unstemmed | Advances in screening and diagnostic lab-on-chip tools for gynaecological cancers – a review |
| title_short | Advances in screening and diagnostic lab-on-chip tools for gynaecological cancers – a review |
| title_sort | advances in screening and diagnostic lab on chip tools for gynaecological cancers a review |
| topic | Gynaecological cancers lab-on-a-chip (LoC) cancer screening cancer diagnosis microfluidics |
| url | https://www.tandfonline.com/doi/10.1080/21691401.2023.2274047 |
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