Dipeptidyl-peptidase-4 inhibitors in type 2 diabetes and COVID-19: From a potential repurposed agent to a useful treatment option
Dipeptidyl-peptidase-4 inhibitors (DPP-4Is) are very commonly prescribed antidiabetic agents in the treatment of type 2 diabetes owing to its modest ability to reduce blood glucose without ensuing any hypoglycemia and weight gain. Many experts have advised continuing DPP-4Is in patient with type 2 d...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Journal of Diabetology |
| Subjects: | |
| Online Access: | http://www.journalofdiabetology.org/article.asp?issn=2078-7685;year=2020;volume=11;issue=3;spage=131;epage=136;aulast=Singh |
| _version_ | 1818459508299530240 |
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| author | Awadhesh Kumar Singh Ritu Singh |
| author_facet | Awadhesh Kumar Singh Ritu Singh |
| author_sort | Awadhesh Kumar Singh |
| collection | DOAJ |
| description | Dipeptidyl-peptidase-4 inhibitors (DPP-4Is) are very commonly prescribed antidiabetic agents in the treatment of type 2 diabetes owing to its modest ability to reduce blood glucose without ensuing any hypoglycemia and weight gain. Many experts have advised continuing DPP-4Is in patient with type 2 diabetes with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19). In addition, several researchers have proposed DPP-4Is to be used as a repurposed agent for COVID-19 not only for the patients with diabetes but also for those without diabetes. We aimed to review as to what could be the reason behind this approach and how does the use of DPP-4Is alter the outcome in patients with type 2 diabetes and COVID-19. |
| first_indexed | 2024-12-14T23:15:28Z |
| format | Article |
| id | doaj.art-0592c6f0307044e3bc0e18bb5bd16505 |
| institution | Directory Open Access Journal |
| issn | 2078-7685 |
| language | English |
| last_indexed | 2024-12-14T23:15:28Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Diabetology |
| spelling | doaj.art-0592c6f0307044e3bc0e18bb5bd165052022-12-21T22:44:05ZengWolters Kluwer Medknow PublicationsJournal of Diabetology2078-76852020-01-0111313113610.4103/JOD.JOD_53_20Dipeptidyl-peptidase-4 inhibitors in type 2 diabetes and COVID-19: From a potential repurposed agent to a useful treatment optionAwadhesh Kumar SinghRitu SinghDipeptidyl-peptidase-4 inhibitors (DPP-4Is) are very commonly prescribed antidiabetic agents in the treatment of type 2 diabetes owing to its modest ability to reduce blood glucose without ensuing any hypoglycemia and weight gain. Many experts have advised continuing DPP-4Is in patient with type 2 diabetes with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19). In addition, several researchers have proposed DPP-4Is to be used as a repurposed agent for COVID-19 not only for the patients with diabetes but also for those without diabetes. We aimed to review as to what could be the reason behind this approach and how does the use of DPP-4Is alter the outcome in patients with type 2 diabetes and COVID-19.http://www.journalofdiabetology.org/article.asp?issn=2078-7685;year=2020;volume=11;issue=3;spage=131;epage=136;aulast=Singhcoronavirus disease 2019dipeptidyl-peptidase-4 inhibitorsoutcomessevere acute respiratory syndrome coronavirus 2type 2 diabetes |
| spellingShingle | Awadhesh Kumar Singh Ritu Singh Dipeptidyl-peptidase-4 inhibitors in type 2 diabetes and COVID-19: From a potential repurposed agent to a useful treatment option Journal of Diabetology coronavirus disease 2019 dipeptidyl-peptidase-4 inhibitors outcomes severe acute respiratory syndrome coronavirus 2 type 2 diabetes |
| title | Dipeptidyl-peptidase-4 inhibitors in type 2 diabetes and COVID-19: From a potential repurposed agent to a useful treatment option |
| title_full | Dipeptidyl-peptidase-4 inhibitors in type 2 diabetes and COVID-19: From a potential repurposed agent to a useful treatment option |
| title_fullStr | Dipeptidyl-peptidase-4 inhibitors in type 2 diabetes and COVID-19: From a potential repurposed agent to a useful treatment option |
| title_full_unstemmed | Dipeptidyl-peptidase-4 inhibitors in type 2 diabetes and COVID-19: From a potential repurposed agent to a useful treatment option |
| title_short | Dipeptidyl-peptidase-4 inhibitors in type 2 diabetes and COVID-19: From a potential repurposed agent to a useful treatment option |
| title_sort | dipeptidyl peptidase 4 inhibitors in type 2 diabetes and covid 19 from a potential repurposed agent to a useful treatment option |
| topic | coronavirus disease 2019 dipeptidyl-peptidase-4 inhibitors outcomes severe acute respiratory syndrome coronavirus 2 type 2 diabetes |
| url | http://www.journalofdiabetology.org/article.asp?issn=2078-7685;year=2020;volume=11;issue=3;spage=131;epage=136;aulast=Singh |
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