Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers

Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers

Abstract Background Circulating tumor DNA (ctDNA) has been becoming a novel convenient and noninvasive method for dynamically monitoring landscape of genomic information to guild personalized cancer treatment. In this study we comprehensively evaluated the additional value of plasma ctDNA to routine...

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Bibliographic Details
Main Authors: Jianjiang Xie, Weishen Yao, Lingxiu Chen, Wenjun Zhu, Qiang Liu, Geng Geng, Jing Fang, Yang Zhao, Li Xiao, Zhenhua Huang, Jing Zhao
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Cancer
Subjects:
Lung cancer
Next generation sequencing
Plasma
Circulating tumor DNA
Online Access:https://doi.org/10.1186/s12885-023-10674-z

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