Valorization of European Cranberry Bush (<i>Viburnum opulus</i> L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their Phytochemical Composition, Antioxidant, and Antiproliferative Activities
Defatted by supercritical CO<sub>2</sub>, <i>Viburnum opulus</i> berry pomace (VOP) was subjected to consecutive extraction with pressurized ethanol (E) and water (W) and yielded 23% of VOP-E and 8% of VOP-W, respectively. The major phytochemical groups covering 42 identified...
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MDPI AG
2020-10-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/9/10/1413 |
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| author | Lijana Dienaitė Milda Pukalskienė Carolina V. Pereira Ana A. Matias Petras Rimantas Venskutonis |
| author_facet | Lijana Dienaitė Milda Pukalskienė Carolina V. Pereira Ana A. Matias Petras Rimantas Venskutonis |
| author_sort | Lijana Dienaitė |
| collection | DOAJ |
| description | Defatted by supercritical CO<sub>2</sub>, <i>Viburnum opulus</i> berry pomace (VOP) was subjected to consecutive extraction with pressurized ethanol (E) and water (W) and yielded 23% of VOP-E and 8% of VOP-W, respectively. The major phytochemical groups covering 42 identified and quantified constituents in VOP extracts were organic and phenolic acids, iridoids, quercetin and (epi)catechin derivatives, flavalignans, procyanidins, and anthocyanins. The on-line HPLC-DPPH<sup>•</sup>-scavenging assay revealed the presence of numerous antioxidants. VOP-E had a higher total phenolic content, was a stronger antioxidant (equivalent to 0.77, 0.42, and 0.17 g trolox/g in oxygen radical absorbance capacity (ORAC), ABTS, and DPPH assays, respectively), and recovered the major part of phenolics from the pomace; however, both extracts demonstrated similar antioxidant activity in the cellular assay. VOP-E inhibited HT29 cancer cells at non-cytotoxic concentrations. The results of this study revealed that VOP contains valuable phytochemicals possessing antioxidant and antiproliferative activities. Consequently, extracts from VOP substances may be of interest in developing functional ingredients for healthy foods, nutraceuticals, and cosmeceuticals. |
| first_indexed | 2024-03-10T15:49:21Z |
| format | Article |
| id | doaj.art-059cd99ba7ce4597bf49e4b66ddb28ac |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-10T15:49:21Z |
| publishDate | 2020-10-01 |
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| record_format | Article |
| series | Foods |
| spelling | doaj.art-059cd99ba7ce4597bf49e4b66ddb28ac2023-11-20T16:10:49ZengMDPI AGFoods2304-81582020-10-01910141310.3390/foods9101413Valorization of European Cranberry Bush (<i>Viburnum opulus</i> L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their Phytochemical Composition, Antioxidant, and Antiproliferative ActivitiesLijana Dienaitė0Milda Pukalskienė1Carolina V. Pereira2Ana A. Matias3Petras Rimantas Venskutonis4Department of Food Science and Technology, Kaunas University of Technology, Radvilėnų pl. 19, Kaunas LT-50254, LithuaniaDepartment of Food Science and Technology, Kaunas University of Technology, Radvilėnų pl. 19, Kaunas LT-50254, LithuaniaIBET—Instituto de Biologia Experimental e Tecnológica, Food & Health Division Apartado 12, 2780-901 Oeiras, PortugalIBET—Instituto de Biologia Experimental e Tecnológica, Food & Health Division Apartado 12, 2780-901 Oeiras, PortugalDepartment of Food Science and Technology, Kaunas University of Technology, Radvilėnų pl. 19, Kaunas LT-50254, LithuaniaDefatted by supercritical CO<sub>2</sub>, <i>Viburnum opulus</i> berry pomace (VOP) was subjected to consecutive extraction with pressurized ethanol (E) and water (W) and yielded 23% of VOP-E and 8% of VOP-W, respectively. The major phytochemical groups covering 42 identified and quantified constituents in VOP extracts were organic and phenolic acids, iridoids, quercetin and (epi)catechin derivatives, flavalignans, procyanidins, and anthocyanins. The on-line HPLC-DPPH<sup>•</sup>-scavenging assay revealed the presence of numerous antioxidants. VOP-E had a higher total phenolic content, was a stronger antioxidant (equivalent to 0.77, 0.42, and 0.17 g trolox/g in oxygen radical absorbance capacity (ORAC), ABTS, and DPPH assays, respectively), and recovered the major part of phenolics from the pomace; however, both extracts demonstrated similar antioxidant activity in the cellular assay. VOP-E inhibited HT29 cancer cells at non-cytotoxic concentrations. The results of this study revealed that VOP contains valuable phytochemicals possessing antioxidant and antiproliferative activities. Consequently, extracts from VOP substances may be of interest in developing functional ingredients for healthy foods, nutraceuticals, and cosmeceuticals.https://www.mdpi.com/2304-8158/9/10/1413guelder rose berriespomacepressurized liquid extractionantioxidant capacityantiproliferative activityflavonoids |
| spellingShingle | Lijana Dienaitė Milda Pukalskienė Carolina V. Pereira Ana A. Matias Petras Rimantas Venskutonis Valorization of European Cranberry Bush (<i>Viburnum opulus</i> L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their Phytochemical Composition, Antioxidant, and Antiproliferative Activities Foods guelder rose berries pomace pressurized liquid extraction antioxidant capacity antiproliferative activity flavonoids |
| title | Valorization of European Cranberry Bush (<i>Viburnum opulus</i> L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their Phytochemical Composition, Antioxidant, and Antiproliferative Activities |
| title_full | Valorization of European Cranberry Bush (<i>Viburnum opulus</i> L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their Phytochemical Composition, Antioxidant, and Antiproliferative Activities |
| title_fullStr | Valorization of European Cranberry Bush (<i>Viburnum opulus</i> L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their Phytochemical Composition, Antioxidant, and Antiproliferative Activities |
| title_full_unstemmed | Valorization of European Cranberry Bush (<i>Viburnum opulus</i> L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their Phytochemical Composition, Antioxidant, and Antiproliferative Activities |
| title_short | Valorization of European Cranberry Bush (<i>Viburnum opulus</i> L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their Phytochemical Composition, Antioxidant, and Antiproliferative Activities |
| title_sort | valorization of european cranberry bush i viburnum opulus i l berry pomace extracts isolated with pressurized ethanol and water by assessing their phytochemical composition antioxidant and antiproliferative activities |
| topic | guelder rose berries pomace pressurized liquid extraction antioxidant capacity antiproliferative activity flavonoids |
| url | https://www.mdpi.com/2304-8158/9/10/1413 |
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