Transmembrane protein 108 inhibits the proliferation and myelination of oligodendrocyte lineage cells in the corpus callosum

Transmembrane protein 108 inhibits the proliferation and myelination of oligodendrocyte lineage cells in the corpus callosum

Abstract Background Abnormal white matter is a common neurobiological change in bipolar disorder, and dysregulation of myelination in oligodendrocytes (OLs) is the cause. Transmembrane protein 108 (Tmem108), as a susceptible gene of bipolar disorder, is expressed higher in OL lineage cells than any...

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Bibliographic Details
Main Authors: Yongqiang Wu, Yanzi Zhong, Xufeng Liao, Xiangguang Miao, Jianbo Yu, Xinsheng Lai, Yu Zhang, Chaolin Ma, Haili Pan, Shunqi Wang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Molecular Brain
Subjects:
Tmem108
Oligodendrocyte (OL)
Myelination
Corpus callosum (CC)
Bipolar disorder (BD)
Online Access:https://doi.org/10.1186/s13041-022-00918-7

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