Fast mutual exclusivity algorithm nominates potential synthetic lethal gene pairs through brute force matrix product computations
Mutual Exclusivity analysis of genomic aberrations contributes to the exploration of potential synthetic lethal (SL) relationships thus guiding the nomination of specific cancer cells vulnerabilities. When multiple classes of genomic aberrations and large cohorts of patients are interrogated, exhaus...
| Main Authors: | , , , , , |
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| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
Elsevier
2021-01-01
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| סדרה: | Computational and Structural Biotechnology Journal |
| נושאים: | |
| גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S2001037021003329 |