The protective potential and possible mechanism of Phyllanthus amarus Schum. & Thonn. aqueous extract on paracetamol-induced hepatotoxicity in rats

The protective potential and possible mechanism of Phyllanthus amarus Schum. & Thonn. aqueous extract on paracetamol-induced hepatotoxicity in rats

The hepatoprotective potential of Phyllanthus amarus Schum. & Thonn. was studied on paracetamolinduced hepatotoxicity in rats by measuring the levels of serum transaminase (SGOT and SGPT), alkaline phosphatase (ALP) and bilirubin, as well as by histopathological examination of the liver. Further...

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Bibliographic Details
Main Authors: Apichat Muso, Vipavadee Prasartthong, Anupong Nitiruangjaras, Patchara Rattanapirun, Peerarat Thaina, Nisita Bumrungwong, Malinee Wongnawa
Format: Article
Language:English
Published: Prince of Songkla University 2006-05-01
Series:Songklanakarin Journal of Science and Technology (SJST)
Subjects:
Phyllanthus amarus
paracetamol
cytochrome P450
glutathione
antioxidant activity
Online Access:http://www.sjst.psu.ac.th/journal/28_3_pdf/10-Phyllanthusamarus-Schum.pdf

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