Morphological Biomarkers in the Amygdala and Hippocampus of Children and Adults at High Familial Risk for Depression

Morphological Biomarkers in the Amygdala and Hippocampus of Children and Adults at High Familial Risk for Depression

Major Depressive Disorder (MDD) is highly familial, and the hippocampus and amygdala are important in the pathophysiology of MDD. Whether morphological markers of risk for familial depression are present in the hippocampus or amygdala is unknown. We imaged the brains of 148 individuals, aged 6 to 54...

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Bibliographic Details
Main Authors: Bradley S. Peterson, Tejal Kaur, Maria Andrea Baez, Ronald C. Whiteman, Siddhant Sawardekar, Juan Sanchez-Peña, Xuejun Hao, Kristin W. Klahr, Ardesheer Talati, Priya Wickramaratne, Myrna M. Weissman, Ravi Bansal
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Diagnostics
Subjects:
biomarker
endophenotype
surface morphology
familial risk
depression
hippocampus
Online Access:https://www.mdpi.com/2075-4418/12/5/1218

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