Membrane Lipids in the Thyroid Comparing to Those in Non-Endocrine Tissues Are Less Sensitive to Pro-Oxidative Effects of Fenton Reaction Substrates

Membrane Lipids in the Thyroid Comparing to Those in Non-Endocrine Tissues Are Less Sensitive to Pro-Oxidative Effects of Fenton Reaction Substrates

Iron is an essential microelement for the proper functioning of many organs, among others it is required for thyroid hormone synthesis. However, its overload contributes to the increased formation of reactive oxygen species via Fenton chemistry (Fe2++H2O2→Fe3++˙OH + OH−), and it is potentially toxic...

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Bibliographic Details
Main Authors: Jan Stępniak, Aleksandra Rynkowska, Małgorzata Karbownik-Lewińska
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Fenton reaction
lipid peroxidation
oxidative damage
thyroid
melatonin
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.901062/full

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