Contact Allergy Induced by Mango (<i>Mangifera indica</i>): A Relevant Topic?
Introduction: The most common clinical manifestation of mango allergy is contact dermatitis, which can be localized or systemic. The sensitising substances that have long been suspected are alk(en)yl catechols and/or alk(en)yl resorcinols. Methods: We reviewed the original articles published on Pubm...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/57/11/1240 |
| _version_ | 1797509416090599424 |
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| author | Elena Camelia Berghea Mihai Craiu Selda Ali Sabina Loredana Corcea Roxana Silvia Bumbacea |
| author_facet | Elena Camelia Berghea Mihai Craiu Selda Ali Sabina Loredana Corcea Roxana Silvia Bumbacea |
| author_sort | Elena Camelia Berghea |
| collection | DOAJ |
| description | Introduction: The most common clinical manifestation of mango allergy is contact dermatitis, which can be localized or systemic. The sensitising substances that have long been suspected are alk(en)yl catechols and/or alk(en)yl resorcinols. Methods: We reviewed the original articles published on Pubmed, Embase and Cochrane Library before 15 September 2021, on the topic of contact allergy induced by mango and we synthesized the key data. Results: We found 12 case reports and four case series, with a total of 37 patients. Only seven of these cases were reported in patients from mango-cultivating countries, the other 30 were from countries where mango cultivation does not occur, and 26 were also from countries where poison ivy/oak are commonly found. We found that contact dermatitis may occur on the first exposure to mango due to previous sensitisation to urushiol-containing plants. The diagnosis was confirmed by patch testing in some of the cases. There was great heterogeneity between the reagents used. Conclusion: Mango fruit is frequently consumed, but mango induced contact dermatitis, the main hypersensitivity reaction induced by mango, is rare. Further data is necessary for a better understanding of sensitising substances and, consecutively, standardization of patch test reagents. |
| first_indexed | 2024-03-10T05:17:23Z |
| format | Article |
| id | doaj.art-05b41028bbd04d9ebcee5d7598edd70c |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-10T05:17:23Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-05b41028bbd04d9ebcee5d7598edd70c2023-11-23T00:17:49ZengMDPI AGMedicina1010-660X1648-91442021-11-015711124010.3390/medicina57111240Contact Allergy Induced by Mango (<i>Mangifera indica</i>): A Relevant Topic?Elena Camelia Berghea0Mihai Craiu1Selda Ali2Sabina Loredana Corcea3Roxana Silvia Bumbacea4Pediatrics Department, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaPediatrics Department, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaAllergology Department, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaPharmacology and Pharmacotherapy Department, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaAllergology Department, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaIntroduction: The most common clinical manifestation of mango allergy is contact dermatitis, which can be localized or systemic. The sensitising substances that have long been suspected are alk(en)yl catechols and/or alk(en)yl resorcinols. Methods: We reviewed the original articles published on Pubmed, Embase and Cochrane Library before 15 September 2021, on the topic of contact allergy induced by mango and we synthesized the key data. Results: We found 12 case reports and four case series, with a total of 37 patients. Only seven of these cases were reported in patients from mango-cultivating countries, the other 30 were from countries where mango cultivation does not occur, and 26 were also from countries where poison ivy/oak are commonly found. We found that contact dermatitis may occur on the first exposure to mango due to previous sensitisation to urushiol-containing plants. The diagnosis was confirmed by patch testing in some of the cases. There was great heterogeneity between the reagents used. Conclusion: Mango fruit is frequently consumed, but mango induced contact dermatitis, the main hypersensitivity reaction induced by mango, is rare. Further data is necessary for a better understanding of sensitising substances and, consecutively, standardization of patch test reagents.https://www.mdpi.com/1648-9144/57/11/1240mango hypersensitivitycontact allergycontact dermatitispatch testingurushiol |
| spellingShingle | Elena Camelia Berghea Mihai Craiu Selda Ali Sabina Loredana Corcea Roxana Silvia Bumbacea Contact Allergy Induced by Mango (<i>Mangifera indica</i>): A Relevant Topic? Medicina mango hypersensitivity contact allergy contact dermatitis patch testing urushiol |
| title | Contact Allergy Induced by Mango (<i>Mangifera indica</i>): A Relevant Topic? |
| title_full | Contact Allergy Induced by Mango (<i>Mangifera indica</i>): A Relevant Topic? |
| title_fullStr | Contact Allergy Induced by Mango (<i>Mangifera indica</i>): A Relevant Topic? |
| title_full_unstemmed | Contact Allergy Induced by Mango (<i>Mangifera indica</i>): A Relevant Topic? |
| title_short | Contact Allergy Induced by Mango (<i>Mangifera indica</i>): A Relevant Topic? |
| title_sort | contact allergy induced by mango i mangifera indica i a relevant topic |
| topic | mango hypersensitivity contact allergy contact dermatitis patch testing urushiol |
| url | https://www.mdpi.com/1648-9144/57/11/1240 |
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