JAK-STAT Pathway Inhibition Partially Restores Intestinal Homeostasis in <i>Hdac1</i>- and <i>Hdac2</i>-Intestinal Epithelial Cell-Deficient Mice
We have previously reported that histone deacetylase epigenetic regulator <i>Hdac1</i> and <i>Hdac2</i> deletion in intestinal epithelial cells (IEC) disrupts mucosal tissue architecture and barrier, causing chronic inflammation. In this study, proteome and transcriptome anal...
Main Authors: | Alexis Gonneaud, Naomie Turgeon, Francois-Michel Boisvert, Francois Boudreau, Claude Asselin |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/2/224 |
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