ROLE OF THYROID DYSFUNCTION IN INFERTILE WOMEN WITH MENSTRUAL DISTURBANCES

Background: Normal thyroid function is necessary to maintain reproductive physiology. An abnormality in its function may be the cause of infertility manifesting as abnormal menstrual cycle. The objective of this study was to find the role of thyroid dysfunction in primary and secondary infertile wom...

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Bibliographic Details
Main Authors: Sabeen Nasir, Muhammad Mumtaz Khan, Sajjad Ahmad, Sadaf Alam, Sara Ziaullah
Format: Article
Language:English
Published: Gomal Medical College, D.I.Khan, Pakistan 2016-12-01
Series:Gomal Journal of Medical Sciences
Subjects:
Online Access:http://gjms.com.pk/ojs24/index.php/gjms/article/view/1245
Description
Summary:Background: Normal thyroid function is necessary to maintain reproductive physiology. An abnormality in its function may be the cause of infertility manifesting as abnormal menstrual cycle. The objective of this study was to find the role of thyroid dysfunction in primary and secondary infertile women with menstrual disturbances. Material & Methods: A total of 168 subjects comprising of 106 primary and 62 secondary infertile women were evaluated. Their detailed clinical and menstrual histories were obtained and their blood samples were taken for thyroid profile. Results: Out of 168 infertile patients 134(79.76%) had euthyroid, 31(18.45%) hyperthyroid and only 3(1.78%) patients had hypothyroid profile. Irregular menstrual cycles were found in 10 out of 31 (32.25%) hyperthyroid, 2 out of 3 (66.66%) hypothyroid and 21 out of 134 (15.67%) euthyroid infertile women. A significant p-value was obtained on comparison of thyroid profile with irregularities in menstrual cycle. Conclusion: It was found that an abnormal thyroid profile may be the cause of infertility in women presenting with menstrual disturbances.
ISSN:1819-7973
1997-2067