ROLE OF THYROID DYSFUNCTION IN INFERTILE WOMEN WITH MENSTRUAL DISTURBANCES

Background: Normal thyroid function is necessary to maintain reproductive physiology. An abnormality in its function may be the cause of infertility manifesting as abnormal menstrual cycle. The objective of this study was to find the role of thyroid dysfunction in primary and secondary infertile wom...

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Main Authors: Sabeen Nasir, Muhammad Mumtaz Khan, Sajjad Ahmad, Sadaf Alam, Sara Ziaullah
Format: Article
Language:English
Published: Gomal Medical College, D.I.Khan, Pakistan 2016-12-01
Series:Gomal Journal of Medical Sciences
Subjects:
Online Access:http://gjms.com.pk/ojs24/index.php/gjms/article/view/1245
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author Sabeen Nasir
Muhammad Mumtaz Khan
Sajjad Ahmad
Sadaf Alam
Sara Ziaullah
author_facet Sabeen Nasir
Muhammad Mumtaz Khan
Sajjad Ahmad
Sadaf Alam
Sara Ziaullah
author_sort Sabeen Nasir
collection DOAJ
description Background: Normal thyroid function is necessary to maintain reproductive physiology. An abnormality in its function may be the cause of infertility manifesting as abnormal menstrual cycle. The objective of this study was to find the role of thyroid dysfunction in primary and secondary infertile women with menstrual disturbances. Material & Methods: A total of 168 subjects comprising of 106 primary and 62 secondary infertile women were evaluated. Their detailed clinical and menstrual histories were obtained and their blood samples were taken for thyroid profile. Results: Out of 168 infertile patients 134(79.76%) had euthyroid, 31(18.45%) hyperthyroid and only 3(1.78%) patients had hypothyroid profile. Irregular menstrual cycles were found in 10 out of 31 (32.25%) hyperthyroid, 2 out of 3 (66.66%) hypothyroid and 21 out of 134 (15.67%) euthyroid infertile women. A significant p-value was obtained on comparison of thyroid profile with irregularities in menstrual cycle. Conclusion: It was found that an abnormal thyroid profile may be the cause of infertility in women presenting with menstrual disturbances.
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spelling doaj.art-05b96625f80049fda7e9c54c6d9f69122022-12-21T23:39:43ZengGomal Medical College, D.I.Khan, PakistanGomal Journal of Medical Sciences1819-79731997-20672016-12-01141856ROLE OF THYROID DYSFUNCTION IN INFERTILE WOMEN WITH MENSTRUAL DISTURBANCESSabeen Nasir0Muhammad Mumtaz Khan1Sajjad Ahmad2Sadaf Alam3Sara Ziaullah4Peshawar Medical College, Riphah International University, IslamabadPeshawar Medical College, Riphah International University, IslamabadPeshawar Medical College, Riphah International University, IslamabadPeshawar Medical College, Riphah International University, IslamabadPeshawar Medical College, Riphah International University, IslamabadBackground: Normal thyroid function is necessary to maintain reproductive physiology. An abnormality in its function may be the cause of infertility manifesting as abnormal menstrual cycle. The objective of this study was to find the role of thyroid dysfunction in primary and secondary infertile women with menstrual disturbances. Material & Methods: A total of 168 subjects comprising of 106 primary and 62 secondary infertile women were evaluated. Their detailed clinical and menstrual histories were obtained and their blood samples were taken for thyroid profile. Results: Out of 168 infertile patients 134(79.76%) had euthyroid, 31(18.45%) hyperthyroid and only 3(1.78%) patients had hypothyroid profile. Irregular menstrual cycles were found in 10 out of 31 (32.25%) hyperthyroid, 2 out of 3 (66.66%) hypothyroid and 21 out of 134 (15.67%) euthyroid infertile women. A significant p-value was obtained on comparison of thyroid profile with irregularities in menstrual cycle. Conclusion: It was found that an abnormal thyroid profile may be the cause of infertility in women presenting with menstrual disturbances.http://gjms.com.pk/ojs24/index.php/gjms/article/view/1245female infertilitythyroid hormonesmenstruation disturbancesmenstrual cyclehpothyroidismhyperthyroidism.
spellingShingle Sabeen Nasir
Muhammad Mumtaz Khan
Sajjad Ahmad
Sadaf Alam
Sara Ziaullah
ROLE OF THYROID DYSFUNCTION IN INFERTILE WOMEN WITH MENSTRUAL DISTURBANCES
Gomal Journal of Medical Sciences
female infertility
thyroid hormones
menstruation disturbances
menstrual cycle
hpothyroidism
hyperthyroidism.
title ROLE OF THYROID DYSFUNCTION IN INFERTILE WOMEN WITH MENSTRUAL DISTURBANCES
title_full ROLE OF THYROID DYSFUNCTION IN INFERTILE WOMEN WITH MENSTRUAL DISTURBANCES
title_fullStr ROLE OF THYROID DYSFUNCTION IN INFERTILE WOMEN WITH MENSTRUAL DISTURBANCES
title_full_unstemmed ROLE OF THYROID DYSFUNCTION IN INFERTILE WOMEN WITH MENSTRUAL DISTURBANCES
title_short ROLE OF THYROID DYSFUNCTION IN INFERTILE WOMEN WITH MENSTRUAL DISTURBANCES
title_sort role of thyroid dysfunction in infertile women with menstrual disturbances
topic female infertility
thyroid hormones
menstruation disturbances
menstrual cycle
hpothyroidism
hyperthyroidism.
url http://gjms.com.pk/ojs24/index.php/gjms/article/view/1245
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AT sajjadahmad roleofthyroiddysfunctionininfertilewomenwithmenstrualdisturbances
AT sadafalam roleofthyroiddysfunctionininfertilewomenwithmenstrualdisturbances
AT saraziaullah roleofthyroiddysfunctionininfertilewomenwithmenstrualdisturbances