JWA suppresses proliferation in trastuzumab-resistant breast cancer by downregulating CDK12
Abstract Breast cancer is the most common cancer worldwide. JWA is a microtubule-associated protein that has been identified as a tumor suppressor, and its downregulation in tumors is an independent adverse prognostic factor. The objective of this study was to explore the expression, regulation, and...
Main Authors: | , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-10-01
|
Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00693-9 |