Comparison of the Average Kappa Coefficients of Binary Diagnostic Tests Done on the Same Subjects

The average kappa coefficient of a binary diagnostic test is a chance corrected index between the binary diagnostic test and the gold standard, and it depends on the sensitivity and the specificity of the diagnostic test and on the disease prevalence. In this article, several hypothesis tests are s...

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Main Authors: José Antonio Roldán-Nofuentes, Carmen Olvera-Porcel
Format: Article
Language:English
Published: Instituto Nacional de Estatística | Statistics Portugal 2018-10-01
Series:Revstat Statistical Journal
Subjects:
Online Access:https://revstat.ine.pt/index.php/REVSTAT/article/view/249
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author José Antonio Roldán-Nofuentes
Carmen Olvera-Porcel
author_facet José Antonio Roldán-Nofuentes
Carmen Olvera-Porcel
author_sort José Antonio Roldán-Nofuentes
collection DOAJ
description The average kappa coefficient of a binary diagnostic test is a chance corrected index between the binary diagnostic test and the gold standard, and it depends on the sensitivity and the specificity of the diagnostic test and on the disease prevalence. In this article, several hypothesis tests are studied to compare the average kappa coefficients of two (o more) binary diagnostic tests done on the same subjects. Simulation experiments were carried out to study the type I errors and the powers of the hypothesis tests studied. A program in R was written to solve the problem studied and it can be freely downloaded from the Internet. The results were applied to a real example on the diagnosis of coronary disease.
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spelling doaj.art-05bbd89da3504954b25f8e499d1af6b22022-12-22T02:17:38ZengInstituto Nacional de Estatística | Statistics PortugalRevstat Statistical Journal1645-67262183-03712018-10-0116410.57805/revstat.v16i4.249Comparison of the Average Kappa Coefficients of Binary Diagnostic Tests Done on the Same SubjectsJosé Antonio Roldán-Nofuentes 0Carmen Olvera-Porcel 1University of GranadaUniversity of Granada The average kappa coefficient of a binary diagnostic test is a chance corrected index between the binary diagnostic test and the gold standard, and it depends on the sensitivity and the specificity of the diagnostic test and on the disease prevalence. In this article, several hypothesis tests are studied to compare the average kappa coefficients of two (o more) binary diagnostic tests done on the same subjects. Simulation experiments were carried out to study the type I errors and the powers of the hypothesis tests studied. A program in R was written to solve the problem studied and it can be freely downloaded from the Internet. The results were applied to a real example on the diagnosis of coronary disease. https://revstat.ine.pt/index.php/REVSTAT/article/view/249average kappa coefficientbinary diagnostic testweighted kappa coefficient
spellingShingle José Antonio Roldán-Nofuentes
Carmen Olvera-Porcel
Comparison of the Average Kappa Coefficients of Binary Diagnostic Tests Done on the Same Subjects
Revstat Statistical Journal
average kappa coefficient
binary diagnostic test
weighted kappa coefficient
title Comparison of the Average Kappa Coefficients of Binary Diagnostic Tests Done on the Same Subjects
title_full Comparison of the Average Kappa Coefficients of Binary Diagnostic Tests Done on the Same Subjects
title_fullStr Comparison of the Average Kappa Coefficients of Binary Diagnostic Tests Done on the Same Subjects
title_full_unstemmed Comparison of the Average Kappa Coefficients of Binary Diagnostic Tests Done on the Same Subjects
title_short Comparison of the Average Kappa Coefficients of Binary Diagnostic Tests Done on the Same Subjects
title_sort comparison of the average kappa coefficients of binary diagnostic tests done on the same subjects
topic average kappa coefficient
binary diagnostic test
weighted kappa coefficient
url https://revstat.ine.pt/index.php/REVSTAT/article/view/249
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