Dexamethasone Induced Osteocyte Apoptosis in Steroid‐Induced Femoral Head Osteonecrosis through ROS‐Mediated Oxidative Stress

Dexamethasone Induced Osteocyte Apoptosis in Steroid‐Induced Femoral Head Osteonecrosis through ROS‐Mediated Oxidative Stress

Objective Glucocorticoid (GC) overuse is strongly associated with steroid‐induced osteonecrosis of the femoral head (SINFH). However, the underlying mechanism of SINFH remains unclear. This study aims to investigate the effect of dexamethasone (Dex)‐induced oxidative stress on osteocyte apoptosis an...

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Bibliographic Details
Main Authors: Xinglong Zhang, Zhenhuan Yang, Qian Xu, Chunlei Xu, Wei Shi, Ran Pang, Kai Zhang, Xinyu Liang, Hui Li, Zhijun Li, Huafeng Zhang
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Orthopaedic Surgery
Subjects:
apoptosis
osteocyte
oxidative stress
reactive oxygen species
steroid‐induced femoral head osteonecrosis
Online Access:https://doi.org/10.1111/os.14010

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