Laminin-integrin a6b4 interaction activates notch signaling to facilitate bladder cancer development

Laminin-integrin a6b4 interaction activates notch signaling to facilitate bladder cancer development

Abstract Background Laminins are high-molecular weight (400 ~ 900 kDa) proteins in extracellular matrix, which serve as major component of the basal lamina, and play a crucial role in promoting tumor cell migration. This study aimed at characterizing the role of laminin in promoting cancer developme...

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Bibliographic Details
Main Authors: Nan Hao, Daming Yang, Tianpei Liu, Shucheng Liu, Xinsheng Lu, Libo Chen
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Cancer
Subjects:
Laminin
Notch signaling
Bladder cancer
Integrins
Online Access:https://doi.org/10.1186/s12885-022-09645-7

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