Recurrent hydatidiform mole: when to stop?

Recurrent hydatidiform mole (RHM) is defined as two or more repeated molar pregnancies in the same patient. Familial recurrent hydatidiform mole (FRHM) is a rare condition in which the patient has relatives with the same condition and mutations. Maternal mutations in the NLRP7 gene are mostly observ...

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Main Authors: E. Ozbasli, O. Takmaz, H. Gurkan, Y. Alanay, M. Gungor, F.S. Dede
Format: Article
Language:English
Published: IMR Press 2020-06-01
Series:Clinical and Experimental Obstetrics & Gynecology
Subjects:
Online Access:https://www.imrpress.com/journal/CEOG/47/3/10.31083/j.ceog.2020.03.5215
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author E. Ozbasli
O. Takmaz
H. Gurkan
Y. Alanay
M. Gungor
F.S. Dede
author_facet E. Ozbasli
O. Takmaz
H. Gurkan
Y. Alanay
M. Gungor
F.S. Dede
author_sort E. Ozbasli
collection DOAJ
description Recurrent hydatidiform mole (RHM) is defined as two or more repeated molar pregnancies in the same patient. Familial recurrent hydatidiform mole (FRHM) is a rare condition in which the patient has relatives with the same condition and mutations. Maternal mutations in the NLRP7 gene are mostly observed in RHM. The authors report a patient from Turkey with a history of seven molar pregnancies who had an aunt with similar obstetric history and NLRP7 mutations.
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spelling doaj.art-05c06775a42c4213b5019d28373dca6b2022-12-22T00:36:37ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632020-06-0147342442610.31083/j.ceog.2020.03.5215S0390-6663(20)00280-8Recurrent hydatidiform mole: when to stop?E. Ozbasli0O. Takmaz1H. Gurkan2Y. Alanay3M. Gungor4F.S. Dede5Department of Obstetrics and Gynecology, Acibadem University School of Medicine, Istanbul, TurkeyDepartment of Obstetrics and Gynecology, Acibadem University School of Medicine, Istanbul, TurkeyDiagnostics Center for Genetic Diseases, University of Trakya, Trakya Medical Faculty, Edirne, TurkeyDepartment of Obstetrics and Gynecology, Acibadem University School of Medicine, Istanbul, TurkeyDepartment of Obstetrics and Gynecology, Acibadem University School of Medicine, Istanbul, TurkeyDepartment of Obstetrics and Gynecology, Acibadem University School of Medicine, Istanbul, TurkeyRecurrent hydatidiform mole (RHM) is defined as two or more repeated molar pregnancies in the same patient. Familial recurrent hydatidiform mole (FRHM) is a rare condition in which the patient has relatives with the same condition and mutations. Maternal mutations in the NLRP7 gene are mostly observed in RHM. The authors report a patient from Turkey with a history of seven molar pregnancies who had an aunt with similar obstetric history and NLRP7 mutations.https://www.imrpress.com/journal/CEOG/47/3/10.31083/j.ceog.2020.03.5215familial hydatidiform molenlrp7ovum donationgenomic imprinting
spellingShingle E. Ozbasli
O. Takmaz
H. Gurkan
Y. Alanay
M. Gungor
F.S. Dede
Recurrent hydatidiform mole: when to stop?
Clinical and Experimental Obstetrics & Gynecology
familial hydatidiform mole
nlrp7
ovum donation
genomic imprinting
title Recurrent hydatidiform mole: when to stop?
title_full Recurrent hydatidiform mole: when to stop?
title_fullStr Recurrent hydatidiform mole: when to stop?
title_full_unstemmed Recurrent hydatidiform mole: when to stop?
title_short Recurrent hydatidiform mole: when to stop?
title_sort recurrent hydatidiform mole when to stop
topic familial hydatidiform mole
nlrp7
ovum donation
genomic imprinting
url https://www.imrpress.com/journal/CEOG/47/3/10.31083/j.ceog.2020.03.5215
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AT hgurkan recurrenthydatidiformmolewhentostop
AT yalanay recurrenthydatidiformmolewhentostop
AT mgungor recurrenthydatidiformmolewhentostop
AT fsdede recurrenthydatidiformmolewhentostop