Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairment
Background The management of modifiable risk factors and comorbidities may impact the future trajectory of cognitive impairment, but easy-to-implement management methods are lacking.Aims This study investigated the effects of simple but comprehensive cognitive health management practices on the cogn...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-08-01
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| Series: | General Psychiatry |
| Online Access: | https://gpsych.bmj.com/content/35/4/e100532.full |
| _version_ | 1811281323685314560 |
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| author | Ling Li Yang Yang Xia Li Shifu Xiao Michael Phillips Jing Nie Yuan Fang Lu Zhao Li Bai Jiayuan Qiu Shaowei Zhang Shixing Qian Meiqing Sheng |
| author_facet | Ling Li Yang Yang Xia Li Shifu Xiao Michael Phillips Jing Nie Yuan Fang Lu Zhao Li Bai Jiayuan Qiu Shaowei Zhang Shixing Qian Meiqing Sheng |
| author_sort | Ling Li |
| collection | DOAJ |
| description | Background The management of modifiable risk factors and comorbidities may impact the future trajectory of cognitive impairment, but easy-to-implement management methods are lacking.Aims This study investigated the effects of simple but comprehensive cognitive health management practices on the cognitive function of older adults in the community with normal cognition (NC) and mild cognitive impairment (MCI).Methods The comprehensive cognitive health management programme included a psychiatric assessment of the cognitive risk factors for those in the intervention groups and individualised recommendations for reducing the risks through self-management supported by regular medical professional follow-up. The intervention groups for this study included 84 elderly participants with NC and 43 elderly participants with MCI who received comprehensive cognitive health management. The control groups included 84 elderly participants with NC and 43 elderly participants with MCI who matched the intervention group’s general characteristics and scale scores using the propensity matching score analysis. The Montreal Cognitive Assessment (MoCA) scale and Geriatric Depression Scale (GDS) scores were compared after a 1-year follow-up.Results For older adults with MCI in the intervention group, MoCA scores were higher at the 1-year follow-up than at baseline (24.07 (3.674) vs 22.21 (3.052), p=0.002). For the MoCA subscales, the intervention group’s abstract and delayed memory scores had significantly increased during the 1-year follow-up. Furthermore, in a generalised linear mixed model analysis, the interaction effect of group×follow-up was statistically significant for the MCI group (F=6.61, p=0.011; coefficients=5.83).Conclusions After the comprehensive cognitive health management intervention, the older adults with MCI in the community showed improvement at the 1-year follow-up. This preliminary study was the first to demonstrate an easy-to-implement strategy for modifying the cognitive risk factors of elderly individuals with MCI in the community, providing new insight into early-stage intervention for dementia. |
| first_indexed | 2024-04-13T01:31:36Z |
| format | Article |
| id | doaj.art-05c1b6417eae408a8154634fc5368995 |
| institution | Directory Open Access Journal |
| issn | 2517-729X |
| language | English |
| last_indexed | 2024-04-13T01:31:36Z |
| publishDate | 2022-08-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | General Psychiatry |
| spelling | doaj.art-05c1b6417eae408a8154634fc53689952022-12-22T03:08:30ZengBMJ Publishing GroupGeneral Psychiatry2517-729X2022-08-0135410.1136/gpsych-2021-100532Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairmentLing Li0Yang Yang1Xia Li2Shifu Xiao3Michael Phillips4Jing Nie5Yuan Fang6Lu Zhao7Li Bai8Jiayuan Qiu9Shaowei Zhang10Shixing Qian11Meiqing Sheng12Department of Endocrinology and Metabolism, Chinese Evidence-based Medicine Centre, Cochrane China Centre, and MAGIC China Centre, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Radiology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaDepartment of Radiotherapy, Cancer Hospital of China Medical University, Shenyang, Liaoning, ChinaAlzheimer’s Disease and Related Disorders Center, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Medicine, Division of Infectious Diseases, NYU Grossman School of Medicine, New York, NY, USADepartment of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China1 Clinical Trial Center, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Cancer Hospital Chinese Academy of Medical Sciences, Chaoyang District, Beijing, ChinaDepartment of Ophthalmology, Beijing Ophthalmology and Visual Science Key laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical Unversity, Beijing, Chinasenior epidemiologistDepartment of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaBackground The management of modifiable risk factors and comorbidities may impact the future trajectory of cognitive impairment, but easy-to-implement management methods are lacking.Aims This study investigated the effects of simple but comprehensive cognitive health management practices on the cognitive function of older adults in the community with normal cognition (NC) and mild cognitive impairment (MCI).Methods The comprehensive cognitive health management programme included a psychiatric assessment of the cognitive risk factors for those in the intervention groups and individualised recommendations for reducing the risks through self-management supported by regular medical professional follow-up. The intervention groups for this study included 84 elderly participants with NC and 43 elderly participants with MCI who received comprehensive cognitive health management. The control groups included 84 elderly participants with NC and 43 elderly participants with MCI who matched the intervention group’s general characteristics and scale scores using the propensity matching score analysis. The Montreal Cognitive Assessment (MoCA) scale and Geriatric Depression Scale (GDS) scores were compared after a 1-year follow-up.Results For older adults with MCI in the intervention group, MoCA scores were higher at the 1-year follow-up than at baseline (24.07 (3.674) vs 22.21 (3.052), p=0.002). For the MoCA subscales, the intervention group’s abstract and delayed memory scores had significantly increased during the 1-year follow-up. Furthermore, in a generalised linear mixed model analysis, the interaction effect of group×follow-up was statistically significant for the MCI group (F=6.61, p=0.011; coefficients=5.83).Conclusions After the comprehensive cognitive health management intervention, the older adults with MCI in the community showed improvement at the 1-year follow-up. This preliminary study was the first to demonstrate an easy-to-implement strategy for modifying the cognitive risk factors of elderly individuals with MCI in the community, providing new insight into early-stage intervention for dementia.https://gpsych.bmj.com/content/35/4/e100532.full |
| spellingShingle | Ling Li Yang Yang Xia Li Shifu Xiao Michael Phillips Jing Nie Yuan Fang Lu Zhao Li Bai Jiayuan Qiu Shaowei Zhang Shixing Qian Meiqing Sheng Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairment General Psychiatry |
| title | Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairment |
| title_full | Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairment |
| title_fullStr | Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairment |
| title_full_unstemmed | Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairment |
| title_short | Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairment |
| title_sort | efficacy of comprehensive cognitive health management for shanghai community older adults with mild cognitive impairment |
| url | https://gpsych.bmj.com/content/35/4/e100532.full |
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