Dynamics of hospitalizations and in-hospital deaths from COVID-19 in northeast Brazil: a retrospective analysis based on the circulation of SARS-CoV-2 variants and vaccination coverage
This study investigated the dynamics of hospitalizations and in-hospital deaths from coronavirus disease 2019 (COVID-19) throughout the pandemic in northeast Brazil, the Brazilian region with the worst socioeconomic indicators. In total, 141,445 cases, 8,213 hospital admissions, and 1,644 in-hospita...
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| Format: | Article |
| Language: | English |
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Korean Society of Epidemiology
2022-04-01
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| Series: | Epidemiology and Health |
| Subjects: | |
| Online Access: | http://www.e-epih.org/upload/epih-44-e2022036.pdf |
| _version_ | 1797768317177430016 |
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| author | Paulo Ricardo Martins-Filho Adriano Antunes de Souza Araújo Lucindo José Quintans-Júnior Bárbara dos Santos Soares Waneska de Souza Barboza Taise Ferreira Cavalcante Victor Santana Santos |
| author_facet | Paulo Ricardo Martins-Filho Adriano Antunes de Souza Araújo Lucindo José Quintans-Júnior Bárbara dos Santos Soares Waneska de Souza Barboza Taise Ferreira Cavalcante Victor Santana Santos |
| author_sort | Paulo Ricardo Martins-Filho |
| collection | DOAJ |
| description | This study investigated the dynamics of hospitalizations and in-hospital deaths from coronavirus disease 2019 (COVID-19) throughout the pandemic in northeast Brazil, the Brazilian region with the worst socioeconomic indicators. In total, 141,445 cases, 8,213 hospital admissions, and 1,644 in-hospital deaths from COVID-19 were registered from March 14, 2020 to February 5, 2022. The overall rates of hospitalization and in-hospital deaths were 5.8% and 20.0%, respectively. The hospitalization and death rates significantly decreased over time, which may have been related to progress in vaccination. During the spread of the Gamma variant (January to June 2021), most hospitalized individuals were young adults, and approximately 40% of deaths occurred in this age group. During the predominance of Delta (July to December 2021), over 75% of deaths occurred among the elderly and unvaccinated or partially vaccinated individuals. This rate decreased to 42.3% during the transmission of the Omicron variant (January to February 2022), during which 34.6% of deaths were recorded among fully vaccinated individuals (2 doses) and 23.1% among those who received full vaccination and a booster. The Omicron-driven third wave was associated with a rise in the proportion of deaths among vaccinated individuals, especially among those who had not received a booster dose. |
| first_indexed | 2024-03-12T20:52:46Z |
| format | Article |
| id | doaj.art-05c200d168de4ccea024aa2691d3c8e7 |
| institution | Directory Open Access Journal |
| issn | 2092-7193 |
| language | English |
| last_indexed | 2024-03-12T20:52:46Z |
| publishDate | 2022-04-01 |
| publisher | Korean Society of Epidemiology |
| record_format | Article |
| series | Epidemiology and Health |
| spelling | doaj.art-05c200d168de4ccea024aa2691d3c8e72023-08-01T00:41:57ZengKorean Society of EpidemiologyEpidemiology and Health2092-71932022-04-014410.4178/epih.e20220361284Dynamics of hospitalizations and in-hospital deaths from COVID-19 in northeast Brazil: a retrospective analysis based on the circulation of SARS-CoV-2 variants and vaccination coveragePaulo Ricardo Martins-Filho0Adriano Antunes de Souza Araújo1Lucindo José Quintans-Júnior2Bárbara dos Santos Soares3Waneska de Souza Barboza4Taise Ferreira Cavalcante5Victor Santana Santos6 Federal University of Sergipe, Sergipe, Brazil Federal University of Sergipe, Sergipe, Brazil Federal University of Sergipe, Sergipe, Brazil Federal University of Sergipe, Sergipe, Brazil Municipal Health Department, Aracaju City Hall, Sergipe, Brazil Federal University of Sergipe, Sergipe, Brazil Federal University of Alagoas, Alagoas, BrazilThis study investigated the dynamics of hospitalizations and in-hospital deaths from coronavirus disease 2019 (COVID-19) throughout the pandemic in northeast Brazil, the Brazilian region with the worst socioeconomic indicators. In total, 141,445 cases, 8,213 hospital admissions, and 1,644 in-hospital deaths from COVID-19 were registered from March 14, 2020 to February 5, 2022. The overall rates of hospitalization and in-hospital deaths were 5.8% and 20.0%, respectively. The hospitalization and death rates significantly decreased over time, which may have been related to progress in vaccination. During the spread of the Gamma variant (January to June 2021), most hospitalized individuals were young adults, and approximately 40% of deaths occurred in this age group. During the predominance of Delta (July to December 2021), over 75% of deaths occurred among the elderly and unvaccinated or partially vaccinated individuals. This rate decreased to 42.3% during the transmission of the Omicron variant (January to February 2022), during which 34.6% of deaths were recorded among fully vaccinated individuals (2 doses) and 23.1% among those who received full vaccination and a booster. The Omicron-driven third wave was associated with a rise in the proportion of deaths among vaccinated individuals, especially among those who had not received a booster dose.http://www.e-epih.org/upload/epih-44-e2022036.pdfcovid-19sars-cov-2sars-cov-2 variantscovid-19 vaccines |
| spellingShingle | Paulo Ricardo Martins-Filho Adriano Antunes de Souza Araújo Lucindo José Quintans-Júnior Bárbara dos Santos Soares Waneska de Souza Barboza Taise Ferreira Cavalcante Victor Santana Santos Dynamics of hospitalizations and in-hospital deaths from COVID-19 in northeast Brazil: a retrospective analysis based on the circulation of SARS-CoV-2 variants and vaccination coverage Epidemiology and Health covid-19 sars-cov-2 sars-cov-2 variants covid-19 vaccines |
| title | Dynamics of hospitalizations and in-hospital deaths from COVID-19 in northeast Brazil: a retrospective analysis based on the circulation of SARS-CoV-2 variants and vaccination coverage |
| title_full | Dynamics of hospitalizations and in-hospital deaths from COVID-19 in northeast Brazil: a retrospective analysis based on the circulation of SARS-CoV-2 variants and vaccination coverage |
| title_fullStr | Dynamics of hospitalizations and in-hospital deaths from COVID-19 in northeast Brazil: a retrospective analysis based on the circulation of SARS-CoV-2 variants and vaccination coverage |
| title_full_unstemmed | Dynamics of hospitalizations and in-hospital deaths from COVID-19 in northeast Brazil: a retrospective analysis based on the circulation of SARS-CoV-2 variants and vaccination coverage |
| title_short | Dynamics of hospitalizations and in-hospital deaths from COVID-19 in northeast Brazil: a retrospective analysis based on the circulation of SARS-CoV-2 variants and vaccination coverage |
| title_sort | dynamics of hospitalizations and in hospital deaths from covid 19 in northeast brazil a retrospective analysis based on the circulation of sars cov 2 variants and vaccination coverage |
| topic | covid-19 sars-cov-2 sars-cov-2 variants covid-19 vaccines |
| url | http://www.e-epih.org/upload/epih-44-e2022036.pdf |
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