Surveillance of bloodstream infections in pediatric cancer centers – what have we learned and how do we move on?

Pediatric patients receiving conventional chemotherapy for malignant disease face an increased risk of bloodstream infection (BSI). Since BSI may represent an acute life-threatening event in patients with profound immunosuppression, and show further negative impact on quality of life and anticancer...

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Main Authors: Simon, Arne, Furtwängler, Rhoikos, Graf, Norbert, Laws, Hans Jürgen, Voigt, Sebastian, Piening, Brar, Geffers, Christine, Agyeman, Philipp, Ammann, Roland A.
Format: Article
Language:deu
Published: German Medical Science GMS Publishing House 2016-05-01
Series:GMS Hygiene and Infection Control
Subjects:
Online Access:http://www.egms.de/static/en/journals/dgkh/2016-11/dgkh000271.shtml
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author Simon, Arne
Furtwängler, Rhoikos
Graf, Norbert
Laws, Hans Jürgen
Voigt, Sebastian
Piening, Brar
Geffers, Christine
Agyeman, Philipp
Ammann, Roland A.
author_facet Simon, Arne
Furtwängler, Rhoikos
Graf, Norbert
Laws, Hans Jürgen
Voigt, Sebastian
Piening, Brar
Geffers, Christine
Agyeman, Philipp
Ammann, Roland A.
author_sort Simon, Arne
collection DOAJ
description Pediatric patients receiving conventional chemotherapy for malignant disease face an increased risk of bloodstream infection (BSI). Since BSI may represent an acute life-threatening event in patients with profound immunosuppression, and show further negative impact on quality of life and anticancer treatment, the prevention of BSI is of paramount importance to improve and guarantee patients’ safety during intensive treatment. The great majority of all pediatric cancer patients (about 85%) have a long-term central venous access catheter in use (type Broviac or Port; CVAD). Referring to the current surveillance definitions a significant proportion of all BSI in pediatric patients with febrile neutropenia is categorized as CVAD- BSI. This state of the art review summarizes the epidemiology and the distinct pathogen profile of BSI in pediatric cancer patients from the perspective of infection surveillance. Problems in executing the current surveillance definition in this patient population are discussed and a new concept for the surveillance of BSI in pediatric cancer patients is outlined.
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spelling doaj.art-05c7a3beb63b4dd78b529dab74d2fbfb2022-12-21T23:19:04ZdeuGerman Medical Science GMS Publishing HouseGMS Hygiene and Infection Control2196-52262016-05-0111Doc1110.3205/dgkh000271Surveillance of bloodstream infections in pediatric cancer centers – what have we learned and how do we move on?Simon, Arne0Furtwängler, Rhoikos1Graf, Norbert2Laws, Hans Jürgen3Voigt, Sebastian4Piening, Brar5Geffers, Christine6Agyeman, Philipp7Ammann, Roland A.8Pädiatrische Onkologie und Hämatologie, Universitätsklinikum des Saarlandes, Homburg, GermanyPädiatrische Onkologie und Hämatologie, Universitätsklinikum des Saarlandes, Homburg, GermanyPädiatrische Onkologie und Hämatologie, Universitätsklinikum des Saarlandes, Homburg, GermanyKlinik für Pädiatrische Onkologie, Hämatologie und Immunologie, Universitätskinderklinik, Heinrich-Heine-Universität, Düsseldorf, GermanyKlinik für Pädiatrie m. S. Onkologie / Hämatologie / Stammzelltransplantation, Charité – Universitätsmedizin Berlin, GermanyInstitut für Hygiene und Umweltmedizin, Charité – Universitätsmedizin Berlin, GermanyInstitut für Hygiene und Umweltmedizin, Charité – Universitätsmedizin Berlin, GermanyPädiatrische Infektiologie und Pädiatrische Hämatologie-Onkologie, Universitätsklinik für Kinderheilkunde, Inselspital, Bern, SwitzerlandPädiatrische Infektiologie und Pädiatrische Hämatologie-Onkologie, Universitätsklinik für Kinderheilkunde, Inselspital, Bern, SwitzerlandPediatric patients receiving conventional chemotherapy for malignant disease face an increased risk of bloodstream infection (BSI). Since BSI may represent an acute life-threatening event in patients with profound immunosuppression, and show further negative impact on quality of life and anticancer treatment, the prevention of BSI is of paramount importance to improve and guarantee patients’ safety during intensive treatment. The great majority of all pediatric cancer patients (about 85%) have a long-term central venous access catheter in use (type Broviac or Port; CVAD). Referring to the current surveillance definitions a significant proportion of all BSI in pediatric patients with febrile neutropenia is categorized as CVAD- BSI. This state of the art review summarizes the epidemiology and the distinct pathogen profile of BSI in pediatric cancer patients from the perspective of infection surveillance. Problems in executing the current surveillance definition in this patient population are discussed and a new concept for the surveillance of BSI in pediatric cancer patients is outlined.http://www.egms.de/static/en/journals/dgkh/2016-11/dgkh000271.shtmlpediatric oncologybloodstream infectionBroviacPortsurveillance
spellingShingle Simon, Arne
Furtwängler, Rhoikos
Graf, Norbert
Laws, Hans Jürgen
Voigt, Sebastian
Piening, Brar
Geffers, Christine
Agyeman, Philipp
Ammann, Roland A.
Surveillance of bloodstream infections in pediatric cancer centers – what have we learned and how do we move on?
GMS Hygiene and Infection Control
pediatric oncology
bloodstream infection
Broviac
Port
surveillance
title Surveillance of bloodstream infections in pediatric cancer centers – what have we learned and how do we move on?
title_full Surveillance of bloodstream infections in pediatric cancer centers – what have we learned and how do we move on?
title_fullStr Surveillance of bloodstream infections in pediatric cancer centers – what have we learned and how do we move on?
title_full_unstemmed Surveillance of bloodstream infections in pediatric cancer centers – what have we learned and how do we move on?
title_short Surveillance of bloodstream infections in pediatric cancer centers – what have we learned and how do we move on?
title_sort surveillance of bloodstream infections in pediatric cancer centers what have we learned and how do we move on
topic pediatric oncology
bloodstream infection
Broviac
Port
surveillance
url http://www.egms.de/static/en/journals/dgkh/2016-11/dgkh000271.shtml
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