Reducing False Negative PCR Test for COVID-19
As the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. Real-time polymerase chain reaction (RT-PCR) is a common molecular test for diagnosing SARS-CoV-2. If some factors are not t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Global Health and Education Projects, Inc.
2020-10-01
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| Series: | International Journal of Maternal and Child Health and AIDS |
| Online Access: | https://mchandaids.org/index.php/IJMA/article/view/421 |
| _version_ | 1818787491198533632 |
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| author | Fatemeh Bahreini, PhD Rezvan Najafi, PhD Razieh Amini, PhD Salman Khazaei, PhD Saeid Bashirian, PhD |
| author_facet | Fatemeh Bahreini, PhD Rezvan Najafi, PhD Razieh Amini, PhD Salman Khazaei, PhD Saeid Bashirian, PhD |
| author_sort | Fatemeh Bahreini, PhD |
| collection | DOAJ |
| description | As the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. Real-time polymerase chain reaction (RT-PCR) is a common molecular test for diagnosing SARS-CoV-2. If some factors are not taken into consideration when performing this test, it can have a relatively large number of false negative results. In this article, we discuss important considerations that could lead to false negative test reduction.
Key words: • SARS-CoV-2 • COVID-19 • Real time polymerase chain reaction • RT-PCR test • Diagnosis • False negatives • Genetics • Emerging disease
Copyright © 2020 Bahreini et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0)which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in this journal, is properly cited. |
| first_indexed | 2024-12-18T14:08:37Z |
| format | Article |
| id | doaj.art-05c99f210f2a4b8b87a8f095f7d9d7ac |
| institution | Directory Open Access Journal |
| issn | 2161-8674 2161-864X |
| language | English |
| last_indexed | 2024-12-18T14:08:37Z |
| publishDate | 2020-10-01 |
| publisher | Global Health and Education Projects, Inc. |
| record_format | Article |
| series | International Journal of Maternal and Child Health and AIDS |
| spelling | doaj.art-05c99f210f2a4b8b87a8f095f7d9d7ac2022-12-21T21:05:10ZengGlobal Health and Education Projects, Inc.International Journal of Maternal and Child Health and AIDS2161-86742161-864X2020-10-019310.21106/ijma.421Reducing False Negative PCR Test for COVID-19Fatemeh Bahreini, PhD0Rezvan Najafi, PhD1Razieh Amini, PhD2Salman Khazaei, PhD3Saeid Bashirian, PhD4Department of Molecular Medicine and Genetics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, IranResearch Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, IranResearch Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, IranModeling of Non-communicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, IranDepartment of Public Health, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IranAs the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. Real-time polymerase chain reaction (RT-PCR) is a common molecular test for diagnosing SARS-CoV-2. If some factors are not taken into consideration when performing this test, it can have a relatively large number of false negative results. In this article, we discuss important considerations that could lead to false negative test reduction. Key words: • SARS-CoV-2 • COVID-19 • Real time polymerase chain reaction • RT-PCR test • Diagnosis • False negatives • Genetics • Emerging disease Copyright © 2020 Bahreini et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0)which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in this journal, is properly cited.https://mchandaids.org/index.php/IJMA/article/view/421 |
| spellingShingle | Fatemeh Bahreini, PhD Rezvan Najafi, PhD Razieh Amini, PhD Salman Khazaei, PhD Saeid Bashirian, PhD Reducing False Negative PCR Test for COVID-19 International Journal of Maternal and Child Health and AIDS |
| title | Reducing False Negative PCR Test for COVID-19 |
| title_full | Reducing False Negative PCR Test for COVID-19 |
| title_fullStr | Reducing False Negative PCR Test for COVID-19 |
| title_full_unstemmed | Reducing False Negative PCR Test for COVID-19 |
| title_short | Reducing False Negative PCR Test for COVID-19 |
| title_sort | reducing false negative pcr test for covid 19 |
| url | https://mchandaids.org/index.php/IJMA/article/view/421 |
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