Numerical Simulation of Fluid Dynamics in a Monolithic Column
As for the measurement of polycyclic aromatic hydrocarbons (PAHs), ultra-performance liquid chromatography (UPLC) is used for PAH identification and densitometry. However, when a solvent containing a substance to be identified passes through a column of UPLC, a dedicated high-pressure-proof device i...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-01-01
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| Series: | Separations |
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| Online Access: | http://www.mdpi.com/2297-8739/4/1/3 |
| _version_ | 1811186461253304320 |
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| author | Kazuhiro Yamamoto Yuuta Tajima |
| author_facet | Kazuhiro Yamamoto Yuuta Tajima |
| author_sort | Kazuhiro Yamamoto |
| collection | DOAJ |
| description | As for the measurement of polycyclic aromatic hydrocarbons (PAHs), ultra-performance liquid chromatography (UPLC) is used for PAH identification and densitometry. However, when a solvent containing a substance to be identified passes through a column of UPLC, a dedicated high-pressure-proof device is required. Recently, a liquid chromatography instrument using a monolithic column technology has been proposed to reduce the pressure of UPLC. The present study tested five types of monolithic columns produced in experiments. To simulate the flow field, the lattice Boltzmann method (LBM) was used. The velocity profile was discussed to decrease the pressure drop in the ultra-performance liquid chromatography (UPLC) system. |
| first_indexed | 2024-04-11T13:45:49Z |
| format | Article |
| id | doaj.art-05cdcfb6760a46568c9ccfdbbea9cc58 |
| institution | Directory Open Access Journal |
| issn | 2297-8739 |
| language | English |
| last_indexed | 2024-04-11T13:45:49Z |
| publishDate | 2017-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Separations |
| spelling | doaj.art-05cdcfb6760a46568c9ccfdbbea9cc582022-12-22T04:21:01ZengMDPI AGSeparations2297-87392017-01-0141310.3390/separations4010003separations4010003Numerical Simulation of Fluid Dynamics in a Monolithic ColumnKazuhiro Yamamoto0Yuuta Tajima1Department of Mechanical Science and Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya-shi, Aichi 464-8603, JapanDepartment of Mechanical Science and Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya-shi, Aichi 464-8603, JapanAs for the measurement of polycyclic aromatic hydrocarbons (PAHs), ultra-performance liquid chromatography (UPLC) is used for PAH identification and densitometry. However, when a solvent containing a substance to be identified passes through a column of UPLC, a dedicated high-pressure-proof device is required. Recently, a liquid chromatography instrument using a monolithic column technology has been proposed to reduce the pressure of UPLC. The present study tested five types of monolithic columns produced in experiments. To simulate the flow field, the lattice Boltzmann method (LBM) was used. The velocity profile was discussed to decrease the pressure drop in the ultra-performance liquid chromatography (UPLC) system.http://www.mdpi.com/2297-8739/4/1/3monolithic columnliquid chromatographyPAHporous structure |
| spellingShingle | Kazuhiro Yamamoto Yuuta Tajima Numerical Simulation of Fluid Dynamics in a Monolithic Column Separations monolithic column liquid chromatography PAH porous structure |
| title | Numerical Simulation of Fluid Dynamics in a Monolithic Column |
| title_full | Numerical Simulation of Fluid Dynamics in a Monolithic Column |
| title_fullStr | Numerical Simulation of Fluid Dynamics in a Monolithic Column |
| title_full_unstemmed | Numerical Simulation of Fluid Dynamics in a Monolithic Column |
| title_short | Numerical Simulation of Fluid Dynamics in a Monolithic Column |
| title_sort | numerical simulation of fluid dynamics in a monolithic column |
| topic | monolithic column liquid chromatography PAH porous structure |
| url | http://www.mdpi.com/2297-8739/4/1/3 |
| work_keys_str_mv | AT kazuhiroyamamoto numericalsimulationoffluiddynamicsinamonolithiccolumn AT yuutatajima numericalsimulationoffluiddynamicsinamonolithiccolumn |