Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE
<p>Abstract</p> <p>Background</p> <p>It has been shown previously that human monocytes fed with haemozoin (HZ) or trophozoite-parasitized RBCs displayed increased matrix metalloproteinase-9 (MMP-9) enzyme activity and protein/mRNA expression and increased TNF production...
Main Authors: | Giribaldi Giuliana, Gallo Valentina, Prato Mauro, Arese Paolo |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2008-08-01
|
Series: | Malaria Journal |
Online Access: | http://www.malariajournal.com/content/7/1/157 |
Similar Items
-
Natural haemozoin induces expression and release of human monocyte tissue inhibitor of metalloproteinase-1.
by: Manuela Polimeni, et al.
Published: (2013-01-01) -
Human lysozyme as a potential diagnostic marker in malaria: a mechanistic study of haemozoin-induced monocyte degranulation
by: Polimeni Manuela, et al.
Published: (2012-10-01) -
Malarial pigment haemozoin, IFN-gamma, TNF-alpha, IL-1beta and LPS do not stimulate expression of inducible nitric oxide synthase and production of nitric oxide in immuno-purified human monocytes
by: Ceretto Monica, et al.
Published: (2007-06-01) -
Early gene expression profiling through a macro-array approach on non-apoptotic human monocytes fed with hemozoin (malarial pigment)
by: Arese Paolo, et al.
Published: (2010-10-01) -
Haemozoin induces early cytokine-mediated lysozyme release from human monocytes through p38 MAPK- and NF-kappaB-dependent mechanisms.
by: Manuela Polimeni, et al.
Published: (2012-01-01)