Perioperative Myocardial Damage and Heart Failure in Noncardiac Surgery. Part 2. Reduction of the Risk of Perioperative Cardiac Complications by Pharmacological Measures and Optimization of Anesthetic and Critical Care Support (Review)

The second part of the overview presents and analyzes the current data on the methods of adjuvant pharmacological cardioprotection and possibilities of optimizing the anesthetic support and perioperative monitoring in high cardiac risk patients. Amendments made in international guidelines for the la...

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Main Authors: I. A. Kozlov, A. M. Ovezov, E. L. Petrovskaya
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2019-07-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1777
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author I. A. Kozlov
A. M. Ovezov
E. L. Petrovskaya
author_facet I. A. Kozlov
A. M. Ovezov
E. L. Petrovskaya
author_sort I. A. Kozlov
collection DOAJ
description The second part of the overview presents and analyzes the current data on the methods of adjuvant pharmacological cardioprotection and possibilities of optimizing the anesthetic support and perioperative monitoring in high cardiac risk patients. Amendments made in international guidelines for the last 2–3 years on the basis of conclusive studies and meta-analyses have been examined. Cardioprotection mechanisms and information about its implementation in real clinical practice have been analysed. It has been shown that by no means all drugs under discussion can be widely used for prophytlactic purposes. Contemporary evidencebased recommendations concerning the optimization of anesthetic support and perioperative monitoring are given. A conclusion has been made that practical implementation of a comprehensive strategy aimed at reduction of the risk of cardiac complications might ensure decrease of both the incidence of severe cardiac complications and mortality due to them.
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spelling doaj.art-05d458f7342846cdb20183c266a0f0262025-03-02T11:29:37ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102019-07-011538310110.15360/1813-9779-2019-3-83-1011692Perioperative Myocardial Damage and Heart Failure in Noncardiac Surgery. Part 2. Reduction of the Risk of Perioperative Cardiac Complications by Pharmacological Measures and Optimization of Anesthetic and Critical Care Support (Review)I. A. Kozlov0A. M. Ovezov1E. L. Petrovskaya2M. F. Vladimirsky Moscow Regional Research Clinical InstituteM. F. Vladimirsky Moscow Regional Research Clinical InstituteM. F. Vladimirsky Moscow Regional Research Clinical InstituteThe second part of the overview presents and analyzes the current data on the methods of adjuvant pharmacological cardioprotection and possibilities of optimizing the anesthetic support and perioperative monitoring in high cardiac risk patients. Amendments made in international guidelines for the last 2–3 years on the basis of conclusive studies and meta-analyses have been examined. Cardioprotection mechanisms and information about its implementation in real clinical practice have been analysed. It has been shown that by no means all drugs under discussion can be widely used for prophytlactic purposes. Contemporary evidencebased recommendations concerning the optimization of anesthetic support and perioperative monitoring are given. A conclusion has been made that practical implementation of a comprehensive strategy aimed at reduction of the risk of cardiac complications might ensure decrease of both the incidence of severe cardiac complications and mortality due to them.https://www.reanimatology.com/rmt/article/view/1777perioperative cardiac complicationsnon-cardiac surgeriespharmacological cardioprotectioncardioprotection mechanismsmyocardial ischemia prophylaxisanesthetic preconditioning
spellingShingle I. A. Kozlov
A. M. Ovezov
E. L. Petrovskaya
Perioperative Myocardial Damage and Heart Failure in Noncardiac Surgery. Part 2. Reduction of the Risk of Perioperative Cardiac Complications by Pharmacological Measures and Optimization of Anesthetic and Critical Care Support (Review)
Общая реаниматология
perioperative cardiac complications
non-cardiac surgeries
pharmacological cardioprotection
cardioprotection mechanisms
myocardial ischemia prophylaxis
anesthetic preconditioning
title Perioperative Myocardial Damage and Heart Failure in Noncardiac Surgery. Part 2. Reduction of the Risk of Perioperative Cardiac Complications by Pharmacological Measures and Optimization of Anesthetic and Critical Care Support (Review)
title_full Perioperative Myocardial Damage and Heart Failure in Noncardiac Surgery. Part 2. Reduction of the Risk of Perioperative Cardiac Complications by Pharmacological Measures and Optimization of Anesthetic and Critical Care Support (Review)
title_fullStr Perioperative Myocardial Damage and Heart Failure in Noncardiac Surgery. Part 2. Reduction of the Risk of Perioperative Cardiac Complications by Pharmacological Measures and Optimization of Anesthetic and Critical Care Support (Review)
title_full_unstemmed Perioperative Myocardial Damage and Heart Failure in Noncardiac Surgery. Part 2. Reduction of the Risk of Perioperative Cardiac Complications by Pharmacological Measures and Optimization of Anesthetic and Critical Care Support (Review)
title_short Perioperative Myocardial Damage and Heart Failure in Noncardiac Surgery. Part 2. Reduction of the Risk of Perioperative Cardiac Complications by Pharmacological Measures and Optimization of Anesthetic and Critical Care Support (Review)
title_sort perioperative myocardial damage and heart failure in noncardiac surgery part 2 reduction of the risk of perioperative cardiac complications by pharmacological measures and optimization of anesthetic and critical care support review
topic perioperative cardiac complications
non-cardiac surgeries
pharmacological cardioprotection
cardioprotection mechanisms
myocardial ischemia prophylaxis
anesthetic preconditioning
url https://www.reanimatology.com/rmt/article/view/1777
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