Aggregation in the spotlight

New findings clarify apparently conflicting results about how molecular agents that preserve protein integrity prevent harmful, dense aggregates from forming.

Bibliographic Details
Main Authors: Zihao Wang, Miranda Collier, Justin Benesch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/73586
_version_ 1818024973312196608
author Zihao Wang
Miranda Collier
Justin Benesch
author_facet Zihao Wang
Miranda Collier
Justin Benesch
author_sort Zihao Wang
collection DOAJ
description New findings clarify apparently conflicting results about how molecular agents that preserve protein integrity prevent harmful, dense aggregates from forming.
first_indexed 2024-12-10T04:08:43Z
format Article
id doaj.art-05d6ce4293b6410a90cb3bfc4f997a08
institution Directory Open Access Journal
issn 2050-084X
language English
last_indexed 2024-12-10T04:08:43Z
publishDate 2021-10-01
publisher eLife Sciences Publications Ltd
record_format Article
series eLife
spelling doaj.art-05d6ce4293b6410a90cb3bfc4f997a082022-12-22T02:02:47ZengeLife Sciences Publications LtdeLife2050-084X2021-10-011010.7554/eLife.73586Aggregation in the spotlightZihao Wang0https://orcid.org/0000-0002-6416-996XMiranda Collier1https://orcid.org/0000-0002-1258-3173Justin Benesch2https://orcid.org/0000-0002-1507-3742Department of Chemistry, Oxford University, Oxford, United KingdomDepartment of Biology, Stanford University, Stanford, United StatesDepartment of Chemistry, Oxford University, Oxford, United KingdomNew findings clarify apparently conflicting results about how molecular agents that preserve protein integrity prevent harmful, dense aggregates from forming.https://elifesciences.org/articles/73586molecular condensatesRRMchaperonestime-resolved quantitative XL-MSFUSaging
spellingShingle Zihao Wang
Miranda Collier
Justin Benesch
Aggregation in the spotlight
eLife
molecular condensates
RRM
chaperones
time-resolved quantitative XL-MS
FUS
aging
title Aggregation in the spotlight
title_full Aggregation in the spotlight
title_fullStr Aggregation in the spotlight
title_full_unstemmed Aggregation in the spotlight
title_short Aggregation in the spotlight
title_sort aggregation in the spotlight
topic molecular condensates
RRM
chaperones
time-resolved quantitative XL-MS
FUS
aging
url https://elifesciences.org/articles/73586
work_keys_str_mv AT zihaowang aggregationinthespotlight
AT mirandacollier aggregationinthespotlight
AT justinbenesch aggregationinthespotlight