Recruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparum.

Recruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparum.

Histone modifications are important regulators of gene expression in all eukaryotes. In Plasmodium falciparum, these epigenetic marks regulate expression of genes involved in several aspects of host-parasite interactions, including antigenic variation. While the identities and genomic positions of m...

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Bibliographic Details
Main Authors: Uchechi E Ukaegbu, Sandeep P Kishore, Dacia L Kwiatkowski, Chethan Pandarinath, Noa Dahan-Pasternak, Ron Dzikowski, Kirk W Deitsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3879369?pdf=render

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