CHANGES IN THE COURSE OF TUBERCULOSIS IN THE PATIENTS WITH DIFFERENT PSYCHOLOGICAL STATUS
The objective of the study: to investigate the changes in the course of tuberculosis in the patients with different psychological status.Subjects and methods. The changes in the course of tuberculosis were studied in 249 new pulmonary tuberculosis patients who had in-patient treatment in CTRI. The g...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2018-08-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1147 |
| _version_ | 1797700239198519296 |
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| author | Natalya V. Zolotova Galina V. Baranova Vladimir V. Streltsov Nadezhda Yu. Kharitonova Tatevik R. Bagdasaryan Anzhela S. Polyakova |
| author_facet | Natalya V. Zolotova Galina V. Baranova Vladimir V. Streltsov Nadezhda Yu. Kharitonova Tatevik R. Bagdasaryan Anzhela S. Polyakova |
| author_sort | Natalya V. Zolotova |
| collection | DOAJ |
| description | The objective of the study: to investigate the changes in the course of tuberculosis in the patients with different psychological status.Subjects and methods. The changes in the course of tuberculosis were studied in 249 new pulmonary tuberculosis patients who had in-patient treatment in CTRI. The groups within the study were formed basing on the results of psychological status assessment: Group 1 included patients with favorable psychological status (171; 68.7% of patients) and Group 2 included patients with different psychological disorders (78; 31.3% of patients) (p < 0.001). Among patients from Group 2 women (66; 84.6%) significantly prevailed over men (12; 15.4%) (< 0.001).Results. It has been found out that groups with different psychological status did not confidently differ in their clinical and X-ray signs before the treatment start. Whereby, in patients from Group 2 versus patients from Group 1, the abnormalities in the results of laboratory tests were registered confidently more often (87.2 versus 75.4% cases) (p < 0.05), as well as multiple drug resistance (58 versus 41.4% of cases) (p < 0.05). The frequency of adverse events caused by anti-tuberculosis drugs was higher in Group 2 versus Group 1 (25; 32.1% and 28; 16.4% of cases) (p < 0.05). After management of adverse events, the number of patients with poor tolerance was still confidently higher in Group 2 (14; 17.9% of cases), compared to Group 1 (11; 6.4%) (p < 0.05). It was found out that the efficiency of in-patient treatment did not confidently differ in the patients with different psychological status. |
| first_indexed | 2024-03-12T04:18:37Z |
| format | Article |
| id | doaj.art-05dc0d99b2634be78b455623bfea55a6 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2024-03-12T04:18:37Z |
| publishDate | 2018-08-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-05dc0d99b2634be78b455623bfea55a62023-09-03T10:34:21ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062018-08-01967333810.21292/2075-1230-2018-96-7-33-381147CHANGES IN THE COURSE OF TUBERCULOSIS IN THE PATIENTS WITH DIFFERENT PSYCHOLOGICAL STATUSNatalya V. Zolotova0Galina V. Baranova1Vladimir V. Streltsov2Nadezhda Yu. Kharitonova3Tatevik R. Bagdasaryan4Anzhela S. Polyakova5ФГБНУ «Центральный НИИ туберкулеза»ФГБНУ «Центральный НИИ туберкулеза»ФГБНУ «Центральный НИИ туберкулеза»ФГБНУ «Центральный НИИ туберкулеза»ФГБНУ «Центральный НИИ туберкулеза»ФГБНУ «Центральный НИИ туберкулеза»The objective of the study: to investigate the changes in the course of tuberculosis in the patients with different psychological status.Subjects and methods. The changes in the course of tuberculosis were studied in 249 new pulmonary tuberculosis patients who had in-patient treatment in CTRI. The groups within the study were formed basing on the results of psychological status assessment: Group 1 included patients with favorable psychological status (171; 68.7% of patients) and Group 2 included patients with different psychological disorders (78; 31.3% of patients) (p < 0.001). Among patients from Group 2 women (66; 84.6%) significantly prevailed over men (12; 15.4%) (< 0.001).Results. It has been found out that groups with different psychological status did not confidently differ in their clinical and X-ray signs before the treatment start. Whereby, in patients from Group 2 versus patients from Group 1, the abnormalities in the results of laboratory tests were registered confidently more often (87.2 versus 75.4% cases) (p < 0.05), as well as multiple drug resistance (58 versus 41.4% of cases) (p < 0.05). The frequency of adverse events caused by anti-tuberculosis drugs was higher in Group 2 versus Group 1 (25; 32.1% and 28; 16.4% of cases) (p < 0.05). After management of adverse events, the number of patients with poor tolerance was still confidently higher in Group 2 (14; 17.9% of cases), compared to Group 1 (11; 6.4%) (p < 0.05). It was found out that the efficiency of in-patient treatment did not confidently differ in the patients with different psychological status.https://www.tibl-journal.com/jour/article/view/1147туберкулез легкихпсихологический статуспереносимость противотуберкулезной химиотерапиидинамика туберкулезного процесса |
| spellingShingle | Natalya V. Zolotova Galina V. Baranova Vladimir V. Streltsov Nadezhda Yu. Kharitonova Tatevik R. Bagdasaryan Anzhela S. Polyakova CHANGES IN THE COURSE OF TUBERCULOSIS IN THE PATIENTS WITH DIFFERENT PSYCHOLOGICAL STATUS Туберкулез и болезни лёгких туберкулез легких психологический статус переносимость противотуберкулезной химиотерапии динамика туберкулезного процесса |
| title | CHANGES IN THE COURSE OF TUBERCULOSIS IN THE PATIENTS WITH DIFFERENT PSYCHOLOGICAL STATUS |
| title_full | CHANGES IN THE COURSE OF TUBERCULOSIS IN THE PATIENTS WITH DIFFERENT PSYCHOLOGICAL STATUS |
| title_fullStr | CHANGES IN THE COURSE OF TUBERCULOSIS IN THE PATIENTS WITH DIFFERENT PSYCHOLOGICAL STATUS |
| title_full_unstemmed | CHANGES IN THE COURSE OF TUBERCULOSIS IN THE PATIENTS WITH DIFFERENT PSYCHOLOGICAL STATUS |
| title_short | CHANGES IN THE COURSE OF TUBERCULOSIS IN THE PATIENTS WITH DIFFERENT PSYCHOLOGICAL STATUS |
| title_sort | changes in the course of tuberculosis in the patients with different psychological status |
| topic | туберкулез легких психологический статус переносимость противотуберкулезной химиотерапии динамика туберкулезного процесса |
| url | https://www.tibl-journal.com/jour/article/view/1147 |
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