Impact of Geriatric Nutritional Risk Index and Modified Creatinine Index Combination on Mortality in Hemodialysis Patients
The prognostic impact of the combination of a geriatric nutritional risk index (GRNI) and modified creatinine index, both of which assess nutritious status in hemodialysis patients, has not yet been well investigated thus far. Patients receiving maintenance hemodialysis in our institutes between Feb...
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MDPI AG
2022-02-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/4/801 |
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| author | Hayato Fujioka Tsutomu Koike Teruhiko Imamura Fumihiro Tomoda Kota Kakeshita Hidenori Yamazaki Koichiro Kinugawa |
| author_facet | Hayato Fujioka Tsutomu Koike Teruhiko Imamura Fumihiro Tomoda Kota Kakeshita Hidenori Yamazaki Koichiro Kinugawa |
| author_sort | Hayato Fujioka |
| collection | DOAJ |
| description | The prognostic impact of the combination of a geriatric nutritional risk index (GRNI) and modified creatinine index, both of which assess nutritious status in hemodialysis patients, has not yet been well investigated thus far. Patients receiving maintenance hemodialysis in our institutes between February 2011 and January 2017 were retrospectively included. The baseline GRNI and modified Creatinine index were calculated and the impact of their combination on 5-year all-cause mortality following the index hemodialysis was investigated. A total of 183 patients (68.3 ± 12.4 years, 98 men, hemodialysis duration 97 ± 89 months) were followed from the index hemodialysis for 5.5 years. Mean GNRI was 91.2 and mean modified Creatinine index was 22.2 in men and 19.6 in women. The 5-year survival was significantly stratified by the median values of GNRI and modified Creatinine index (<i>p</i> < 0.05 for both). Patients with low GNRI and a low modified Creatinine index had lower 5-year survival than those with the other three combination patterns (<i>p</i> < 0.05). A combination of GNRI and modified Creatinine index may be a promising tool to risk stratify mortality in dialysis patients. |
| first_indexed | 2024-03-09T21:17:30Z |
| format | Article |
| id | doaj.art-05de563f1c6c4530a7b6e18b87a2434a |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T21:17:30Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
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| spelling | doaj.art-05de563f1c6c4530a7b6e18b87a2434a2023-11-23T21:28:36ZengMDPI AGNutrients2072-66432022-02-0114480110.3390/nu14040801Impact of Geriatric Nutritional Risk Index and Modified Creatinine Index Combination on Mortality in Hemodialysis PatientsHayato Fujioka0Tsutomu Koike1Teruhiko Imamura2Fumihiro Tomoda3Kota Kakeshita4Hidenori Yamazaki5Koichiro Kinugawa6The Second Department of Internal Medicine, Toyama University, Toyama 930-0194, JapanThe Second Department of Internal Medicine, Toyama University, Toyama 930-0194, JapanThe Second Department of Internal Medicine, Toyama University, Toyama 930-0194, JapanFaculty of Health Science, Fukui Health Science University, Fukui 910-3190, JapanThe Second Department of Internal Medicine, Toyama University, Toyama 930-0194, JapanThe Second Department of Internal Medicine, Toyama University, Toyama 930-0194, JapanThe Second Department of Internal Medicine, Toyama University, Toyama 930-0194, JapanThe prognostic impact of the combination of a geriatric nutritional risk index (GRNI) and modified creatinine index, both of which assess nutritious status in hemodialysis patients, has not yet been well investigated thus far. Patients receiving maintenance hemodialysis in our institutes between February 2011 and January 2017 were retrospectively included. The baseline GRNI and modified Creatinine index were calculated and the impact of their combination on 5-year all-cause mortality following the index hemodialysis was investigated. A total of 183 patients (68.3 ± 12.4 years, 98 men, hemodialysis duration 97 ± 89 months) were followed from the index hemodialysis for 5.5 years. Mean GNRI was 91.2 and mean modified Creatinine index was 22.2 in men and 19.6 in women. The 5-year survival was significantly stratified by the median values of GNRI and modified Creatinine index (<i>p</i> < 0.05 for both). Patients with low GNRI and a low modified Creatinine index had lower 5-year survival than those with the other three combination patterns (<i>p</i> < 0.05). A combination of GNRI and modified Creatinine index may be a promising tool to risk stratify mortality in dialysis patients.https://www.mdpi.com/2072-6643/14/4/801malnutritioninflammationend-stage renal disease |
| spellingShingle | Hayato Fujioka Tsutomu Koike Teruhiko Imamura Fumihiro Tomoda Kota Kakeshita Hidenori Yamazaki Koichiro Kinugawa Impact of Geriatric Nutritional Risk Index and Modified Creatinine Index Combination on Mortality in Hemodialysis Patients Nutrients malnutrition inflammation end-stage renal disease |
| title | Impact of Geriatric Nutritional Risk Index and Modified Creatinine Index Combination on Mortality in Hemodialysis Patients |
| title_full | Impact of Geriatric Nutritional Risk Index and Modified Creatinine Index Combination on Mortality in Hemodialysis Patients |
| title_fullStr | Impact of Geriatric Nutritional Risk Index and Modified Creatinine Index Combination on Mortality in Hemodialysis Patients |
| title_full_unstemmed | Impact of Geriatric Nutritional Risk Index and Modified Creatinine Index Combination on Mortality in Hemodialysis Patients |
| title_short | Impact of Geriatric Nutritional Risk Index and Modified Creatinine Index Combination on Mortality in Hemodialysis Patients |
| title_sort | impact of geriatric nutritional risk index and modified creatinine index combination on mortality in hemodialysis patients |
| topic | malnutrition inflammation end-stage renal disease |
| url | https://www.mdpi.com/2072-6643/14/4/801 |
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