SELECTIVE INHIBITION OF KRAS SIGNALING BY COMBINATION OF LOW DOSE RAPAMYCIN AND PACLITAXEL IN VIVO
Background. Therapy with compounds potentially capable to block KRAS oncogene signaling pathway is perspective direction in modern oncopharmacology. The aim of current study was to investigate effects of the combined treatment with rapamycin (RAP) and paclitaxel (PAC) in transgenic zebrafish (Danio...
Main Authors: | M. N. Yurova, D. R. Safina, I. V. Mizgirev |
---|---|
Format: | Article |
Language: | Russian |
Published: |
ABV-press
2018-07-01
|
Series: | Успехи молекулярной онкологии |
Subjects: | |
Online Access: | https://umo.abvpress.ru/jour/article/view/146 |
Similar Items
-
The role of KRAS and NRAS mutation detection in determining the therapy strategy for colorectal cancer
by: A. N. Toropovskiy, et al.
Published: (2022-11-01) -
Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish
by: Yonghe Ding, et al.
Published: (2019-10-01) -
A quantitative modelling approach to zebrafish pigment pattern formation
by: Jennifer P Owen, et al.
Published: (2020-07-01) -
Inhibition of glucocorticoid-induced REDD1 expression by rapamycin in breast cancer cells
by: D. D. Grigorieva, et al.
Published: (2022-03-01) -
Evaluation of Octhylphenol Effect on Development and Survival on Zebra Fish (Danio Rerio) During Different Ontogenic Period
by: Gabi Dumitrescu, et al.
Published: (2023-10-01)