Endosomal PI(3)P regulation by the COMMD/CCDC22/CCDC93 (CCC) complex controls membrane protein recycling
Recycling of proteins that have entered the endosome is essential to homeostasis. The COMMD/CCDC22/CCDC93 (CCC) complex is regulator of recycling but the molecular mechanisms are unclear. Here, the authors report that the CCC complex regulates endosomal recycling by maintaining PI3P levels on endoso...
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Bibliographic Details
| Main Authors: |
Amika Singla,
Alina Fedoseienko,
Sai S. P. Giridharan,
Brittany L. Overlee,
Adam Lopez,
Da Jia,
Jie Song,
Kayci Huff-Hardy,
Lois Weisman,
Ezra Burstein,
Daniel D. Billadeau |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2019-09-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-12221-6
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