Enantioconvergent catalysis
An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%. Three mechanistically distinct approaches to effecting enantioconvergent catalysis are identified, and recent examples of each are...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2016-09-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.12.192 |
| _version_ | 1818451690931617792 |
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| author | Justin T. Mohr Jared T. Moore Brian M. Stoltz |
| author_facet | Justin T. Mohr Jared T. Moore Brian M. Stoltz |
| author_sort | Justin T. Mohr |
| collection | DOAJ |
| description | An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%. Three mechanistically distinct approaches to effecting enantioconvergent catalysis are identified, and recent examples of each are highlighted. These processes are compared to related, non-enantioconvergent methods. |
| first_indexed | 2024-12-14T21:11:13Z |
| format | Article |
| id | doaj.art-05f0fbec54bf4cceb0823eeed12f3fc6 |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-12-14T21:11:13Z |
| publishDate | 2016-09-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-05f0fbec54bf4cceb0823eeed12f3fc62022-12-21T22:47:13ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972016-09-011212038204510.3762/bjoc.12.1921860-5397-12-192Enantioconvergent catalysisJustin T. Mohr0Jared T. Moore1Brian M. Stoltz2Department of Chemistry, University of Illinois at Chicago, 845 West Taylor St., Chicago, IL 60607, USAThe Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering, Division of Chemistry and Chemical Engineering California Institute of Technology, 1200 E California Blvd. MC 101-20, Pasadena, CA 91125, USA, Fax: (+1) 626-395-8436The Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering, Division of Chemistry and Chemical Engineering California Institute of Technology, 1200 E California Blvd. MC 101-20, Pasadena, CA 91125, USA, Fax: (+1) 626-395-8436An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%. Three mechanistically distinct approaches to effecting enantioconvergent catalysis are identified, and recent examples of each are highlighted. These processes are compared to related, non-enantioconvergent methods.https://doi.org/10.3762/bjoc.12.192asymmetric catalysisenantioselectivitysynthetic methods |
| spellingShingle | Justin T. Mohr Jared T. Moore Brian M. Stoltz Enantioconvergent catalysis Beilstein Journal of Organic Chemistry asymmetric catalysis enantioselectivity synthetic methods |
| title | Enantioconvergent catalysis |
| title_full | Enantioconvergent catalysis |
| title_fullStr | Enantioconvergent catalysis |
| title_full_unstemmed | Enantioconvergent catalysis |
| title_short | Enantioconvergent catalysis |
| title_sort | enantioconvergent catalysis |
| topic | asymmetric catalysis enantioselectivity synthetic methods |
| url | https://doi.org/10.3762/bjoc.12.192 |
| work_keys_str_mv | AT justintmohr enantioconvergentcatalysis AT jaredtmoore enantioconvergentcatalysis AT brianmstoltz enantioconvergentcatalysis |