Comparative data of the revelation of lupous anticoagulant effects with Russell viper and Central Asian gyurza venoms

For identification of lupous anticoagulant (LA) effects tests with phospholipin-dependent coagulase of snake venoms are used. Abroad they use the diluted Russell viper venom for this purpose.Investigations carried out by the authors on 31 patients (10 men and 21 women) aged 25-51 with antiphospholip...

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Main Authors: Z. S. Barkagan, G. V. Serdyuk, L. P. Tsyvkina, A. P. Momot
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2004-03-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/3597
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author Z. S. Barkagan
G. V. Serdyuk
L. P. Tsyvkina
A. P. Momot
author_facet Z. S. Barkagan
G. V. Serdyuk
L. P. Tsyvkina
A. P. Momot
author_sort Z. S. Barkagan
collection DOAJ
description For identification of lupous anticoagulant (LA) effects tests with phospholipin-dependent coagulase of snake venoms are used. Abroad they use the diluted Russell viper venom for this purpose.Investigations carried out by the authors on 31 patients (10 men and 21 women) aged 25-51 with antiphospholipin syndrome registered by clinical and laboratory criterions, have shown that the coagulation test with diluted Central Asian gyurza (Vipera lebetina turanica) venom could be used for the same purpose, its coagulase by the action mechanism is close to the coagulase of Russell viper venom (Vipers Russelli).
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spelling doaj.art-05f187b4fcc7454b970509a50aae71bb2023-03-13T09:58:02ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842004-03-0131444610.20538/1682-0363-2004-1-44-462241Comparative data of the revelation of lupous anticoagulant effects with Russell viper and Central Asian gyurza venomsZ. S. Barkagan0G. V. Serdyuk1L. P. Tsyvkina2A. P. Momot3Алтайский государственный медицинский университет; Федеральный академический центр, ЦНИЛ АлГМУАлтайский государственный медицинский университет; Федеральный академический центр, ЦНИЛ АлГМУАлтайский государственный медицинский университет; Федеральный академический центр, ЦНИЛ АлГМУАлтайский государственный медицинский университет; Федеральный академический центр, ЦНИЛ АлГМУFor identification of lupous anticoagulant (LA) effects tests with phospholipin-dependent coagulase of snake venoms are used. Abroad they use the diluted Russell viper venom for this purpose.Investigations carried out by the authors on 31 patients (10 men and 21 women) aged 25-51 with antiphospholipin syndrome registered by clinical and laboratory criterions, have shown that the coagulation test with diluted Central Asian gyurza (Vipera lebetina turanica) venom could be used for the same purpose, its coagulase by the action mechanism is close to the coagulase of Russell viper venom (Vipers Russelli).https://bulletin.ssmu.ru/jour/article/view/3597антифосфолипидный синдромволчаночные антикоагулянтыразведенный яд гюрзы среднеазиатскойразведенный яд гадюки расселлабедная тромбоцитами плазмаантифосфолипидные антитела
spellingShingle Z. S. Barkagan
G. V. Serdyuk
L. P. Tsyvkina
A. P. Momot
Comparative data of the revelation of lupous anticoagulant effects with Russell viper and Central Asian gyurza venoms
Бюллетень сибирской медицины
антифосфолипидный синдром
волчаночные антикоагулянты
разведенный яд гюрзы среднеазиатской
разведенный яд гадюки расселла
бедная тромбоцитами плазма
антифосфолипидные антитела
title Comparative data of the revelation of lupous anticoagulant effects with Russell viper and Central Asian gyurza venoms
title_full Comparative data of the revelation of lupous anticoagulant effects with Russell viper and Central Asian gyurza venoms
title_fullStr Comparative data of the revelation of lupous anticoagulant effects with Russell viper and Central Asian gyurza venoms
title_full_unstemmed Comparative data of the revelation of lupous anticoagulant effects with Russell viper and Central Asian gyurza venoms
title_short Comparative data of the revelation of lupous anticoagulant effects with Russell viper and Central Asian gyurza venoms
title_sort comparative data of the revelation of lupous anticoagulant effects with russell viper and central asian gyurza venoms
topic антифосфолипидный синдром
волчаночные антикоагулянты
разведенный яд гюрзы среднеазиатской
разведенный яд гадюки расселла
бедная тромбоцитами плазма
антифосфолипидные антитела
url https://bulletin.ssmu.ru/jour/article/view/3597
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AT gvserdyuk comparativedataoftherevelationoflupousanticoagulanteffectswithrussellviperandcentralasiangyurzavenoms
AT lptsyvkina comparativedataoftherevelationoflupousanticoagulanteffectswithrussellviperandcentralasiangyurzavenoms
AT apmomot comparativedataoftherevelationoflupousanticoagulanteffectswithrussellviperandcentralasiangyurzavenoms