The effect of consuming oxidized oil supplemented with fiber on lipid profiles in rat model
Background: This study was conducted to evaluate the effects of consuming thermally oxidized oil supplemented with pectin on liver glutathione peroxidase activity, serum malondialdehyde and lipid profiles in male Sprague-Dawley rats. Methods: Fifty growing male Sprague-Dawley rats were randomly divi...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2011-01-01
|
| Series: | Journal of Research in Medical Sciences |
| Subjects: | |
| Online Access: | http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2011;volume=16;issue=12;spage=1541;epage=1549;aulast=Shafaeizadeh |
| _version_ | 1818344612086939648 |
|---|---|
| author | Shila Shafaeizadeh Jalal Jamalian Ali Akbare Owji Leila Azadbakht Roghayeh Ramezani Narges Karbalaei Abdolreza Rajaeifard Negar Tabatabai |
| author_facet | Shila Shafaeizadeh Jalal Jamalian Ali Akbare Owji Leila Azadbakht Roghayeh Ramezani Narges Karbalaei Abdolreza Rajaeifard Negar Tabatabai |
| author_sort | Shila Shafaeizadeh |
| collection | DOAJ |
| description | Background: This study was conducted to evaluate the effects of consuming thermally oxidized oil supplemented with pectin on liver glutathione peroxidase activity, serum malondialdehyde and lipid profiles in male Sprague-Dawley rats.
Methods: Fifty growing male Sprague-Dawley rats were randomly divided into different groups. The diets differed only in their fat and pectin content. The diets had fresh sunflower oil or thermally oxidized sunflower oil. The diets were supplemented with pectin in the amount of 50 g/kg diet or not supplemented. Thus, there were four experimental groups: "fresh oil", "oxidized oil", "fresh oil + pectin", "oxidized oil + pectin". Study duration was 42 days. Non parametric, Kruskal-Wallis and Mann-Whitney tests were used to evaluate mean values of variables in groups.
Results: In oil consumption, peroxide, p- Anisidine, thiobarbituric acid, free fatty acid values and total polar compounds increased but iodine value was decreased. In the oxidized oil group compared to the fresh oil group, total cholesterol, high density lipoprotein cholesterol and malondialdehyde increased (p < 0.05). Serum malondialdehyde was decreased in the "oxidized oil + pectin" group compared to the oxidized oil alone (2.82 ± 0.51 vs. 3.61 ± 0.72 nmol/ml; p < 0.05). Total cholesterol decreased in both groups containing pectin compared to their respective diets without supplementation (70.10 ± 10.75 vs. 81.20 ± 13.10 mg/dl; p < 0.05).
Conclusions: Pectin consumption could decrease serum malondialdehyde and cholesterol in the diet that contains oxidized oil. Pectin supplementation could decrease the detrimental effects of thermally oxidized oil. |
| first_indexed | 2024-12-13T16:49:14Z |
| format | Article |
| id | doaj.art-05f1f65e426a425789d776f72900baf3 |
| institution | Directory Open Access Journal |
| issn | 1735-1995 1735-7136 |
| language | English |
| last_indexed | 2024-12-13T16:49:14Z |
| publishDate | 2011-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Research in Medical Sciences |
| spelling | doaj.art-05f1f65e426a425789d776f72900baf32022-12-21T23:38:05ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362011-01-01161215411549The effect of consuming oxidized oil supplemented with fiber on lipid profiles in rat modelShila ShafaeizadehJalal JamalianAli Akbare OwjiLeila AzadbakhtRoghayeh RamezaniNarges KarbalaeiAbdolreza RajaeifardNegar TabatabaiBackground: This study was conducted to evaluate the effects of consuming thermally oxidized oil supplemented with pectin on liver glutathione peroxidase activity, serum malondialdehyde and lipid profiles in male Sprague-Dawley rats. Methods: Fifty growing male Sprague-Dawley rats were randomly divided into different groups. The diets differed only in their fat and pectin content. The diets had fresh sunflower oil or thermally oxidized sunflower oil. The diets were supplemented with pectin in the amount of 50 g/kg diet or not supplemented. Thus, there were four experimental groups: "fresh oil", "oxidized oil", "fresh oil + pectin", "oxidized oil + pectin". Study duration was 42 days. Non parametric, Kruskal-Wallis and Mann-Whitney tests were used to evaluate mean values of variables in groups. Results: In oil consumption, peroxide, p- Anisidine, thiobarbituric acid, free fatty acid values and total polar compounds increased but iodine value was decreased. In the oxidized oil group compared to the fresh oil group, total cholesterol, high density lipoprotein cholesterol and malondialdehyde increased (p < 0.05). Serum malondialdehyde was decreased in the "oxidized oil + pectin" group compared to the oxidized oil alone (2.82 ± 0.51 vs. 3.61 ± 0.72 nmol/ml; p < 0.05). Total cholesterol decreased in both groups containing pectin compared to their respective diets without supplementation (70.10 ± 10.75 vs. 81.20 ± 13.10 mg/dl; p < 0.05). Conclusions: Pectin consumption could decrease serum malondialdehyde and cholesterol in the diet that contains oxidized oil. Pectin supplementation could decrease the detrimental effects of thermally oxidized oil.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2011;volume=16;issue=12;spage=1541;epage=1549;aulast=ShafaeizadehThermally Oxidized OilPectinMalondialdehydeLipid ProfileLipid Peroxides |
| spellingShingle | Shila Shafaeizadeh Jalal Jamalian Ali Akbare Owji Leila Azadbakht Roghayeh Ramezani Narges Karbalaei Abdolreza Rajaeifard Negar Tabatabai The effect of consuming oxidized oil supplemented with fiber on lipid profiles in rat model Journal of Research in Medical Sciences Thermally Oxidized Oil Pectin Malondialdehyde Lipid Profile Lipid Peroxides |
| title | The effect of consuming oxidized oil supplemented with fiber on lipid profiles in rat model |
| title_full | The effect of consuming oxidized oil supplemented with fiber on lipid profiles in rat model |
| title_fullStr | The effect of consuming oxidized oil supplemented with fiber on lipid profiles in rat model |
| title_full_unstemmed | The effect of consuming oxidized oil supplemented with fiber on lipid profiles in rat model |
| title_short | The effect of consuming oxidized oil supplemented with fiber on lipid profiles in rat model |
| title_sort | effect of consuming oxidized oil supplemented with fiber on lipid profiles in rat model |
| topic | Thermally Oxidized Oil Pectin Malondialdehyde Lipid Profile Lipid Peroxides |
| url | http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2011;volume=16;issue=12;spage=1541;epage=1549;aulast=Shafaeizadeh |
| work_keys_str_mv | AT shilashafaeizadeh theeffectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT jalaljamalian theeffectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT aliakbareowji theeffectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT leilaazadbakht theeffectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT roghayehramezani theeffectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT nargeskarbalaei theeffectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT abdolrezarajaeifard theeffectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT negartabatabai theeffectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT shilashafaeizadeh effectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT jalaljamalian effectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT aliakbareowji effectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT leilaazadbakht effectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT roghayehramezani effectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT nargeskarbalaei effectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT abdolrezarajaeifard effectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel AT negartabatabai effectofconsumingoxidizedoilsupplementedwithfiberonlipidprofilesinratmodel |