Modified Pair Technique for Treatment of Hydatid Cysts in the Spleen

The aim of this study was to evaluate the results of single-session sclerotherapy with mixture of alcohol and polidocanol and a subsequent injection of albendazole for devisceration of hydatid cysts in the spleen. Eight patients (four women and four men, average age 22.9±11.4 with hydatid cyst in t...

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Main Authors: Enver Zerem, Amir Nuhanović, Jasmin Caluk
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2005-08-01
Series:Biomolecules & Biomedicine
Subjects:
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/3275
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author Enver Zerem
Amir Nuhanović
Jasmin Caluk
author_facet Enver Zerem
Amir Nuhanović
Jasmin Caluk
author_sort Enver Zerem
collection DOAJ
description The aim of this study was to evaluate the results of single-session sclerotherapy with mixture of alcohol and polidocanol and a subsequent injection of albendazole for devisceration of hydatid cysts in the spleen. Eight patients (four women and four men, average age 22.9±11.4 with hydatid cyst in the spleen were treated with 10 minutes time of exposure to mixture of ethanol 95% and polidocanol 1%. After that, 2 to 5 ml of albendazole was injected into the cyst cavity. Two patients had 2 cysts. At follow-up the patients were examined with clinical and biochemical examinations, ultrasonography, and serologic test for echinococcal antibody titres. The mean hospital stay was 2.5±0.93 days. During the follow-up period, mean cyst diameter decreased from 46±16.4 mm to 13.6±16.26 mm. In all ten cysts, a reduction of post procedural recolection of fluid over 40% was observed. Five cysts (50%) disappeared during the follow-up period. All cysts (5) smaller then 50 mm in diameter disappeared during follow-up period. After an initial rise, the echinococcal-an-tibody titres fell progressively and at the last follow-up were negative (< 1: 160) in 7 (88%) patients. No complications were observed, except for pain, fever and urticaria during the first 24-hours after the procedure. Sclerotherapy using only one session and 10 min time of exposure to the mixture of ethanol and polidocanol, and a subsequent injection of al-bendasole solution represents an effective treatment of hydatid cysts in the spleen. This procedure is even more efficacious for hydatid cyst with diametar smaller then 50mm.
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spelling doaj.art-05f3e44e318249b2914c9e3da4770a0d2024-03-15T14:42:17ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2005-08-015310.17305/bjbms.2005.3275767Modified Pair Technique for Treatment of Hydatid Cysts in the SpleenEnver Zerem0Amir Nuhanović1Jasmin Caluk2University Clinical center of Tuzla, Internal Clinic, Department of GastroenterologyUniversity Clinical center of Tuzla, Internal Clinic, Department of GastroenterologyUniversity Clinical center of Tuzla, Internal Clinic, Department of Gastroenterology The aim of this study was to evaluate the results of single-session sclerotherapy with mixture of alcohol and polidocanol and a subsequent injection of albendazole for devisceration of hydatid cysts in the spleen. Eight patients (four women and four men, average age 22.9±11.4 with hydatid cyst in the spleen were treated with 10 minutes time of exposure to mixture of ethanol 95% and polidocanol 1%. After that, 2 to 5 ml of albendazole was injected into the cyst cavity. Two patients had 2 cysts. At follow-up the patients were examined with clinical and biochemical examinations, ultrasonography, and serologic test for echinococcal antibody titres. The mean hospital stay was 2.5±0.93 days. During the follow-up period, mean cyst diameter decreased from 46±16.4 mm to 13.6±16.26 mm. In all ten cysts, a reduction of post procedural recolection of fluid over 40% was observed. Five cysts (50%) disappeared during the follow-up period. All cysts (5) smaller then 50 mm in diameter disappeared during follow-up period. After an initial rise, the echinococcal-an-tibody titres fell progressively and at the last follow-up were negative (< 1: 160) in 7 (88%) patients. No complications were observed, except for pain, fever and urticaria during the first 24-hours after the procedure. Sclerotherapy using only one session and 10 min time of exposure to the mixture of ethanol and polidocanol, and a subsequent injection of al-bendasole solution represents an effective treatment of hydatid cysts in the spleen. This procedure is even more efficacious for hydatid cyst with diametar smaller then 50mm. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3275Spleen hydatid cystPAIRInterventional ultrasound
spellingShingle Enver Zerem
Amir Nuhanović
Jasmin Caluk
Modified Pair Technique for Treatment of Hydatid Cysts in the Spleen
Biomolecules & Biomedicine
Spleen hydatid cyst
PAIR
Interventional ultrasound
title Modified Pair Technique for Treatment of Hydatid Cysts in the Spleen
title_full Modified Pair Technique for Treatment of Hydatid Cysts in the Spleen
title_fullStr Modified Pair Technique for Treatment of Hydatid Cysts in the Spleen
title_full_unstemmed Modified Pair Technique for Treatment of Hydatid Cysts in the Spleen
title_short Modified Pair Technique for Treatment of Hydatid Cysts in the Spleen
title_sort modified pair technique for treatment of hydatid cysts in the spleen
topic Spleen hydatid cyst
PAIR
Interventional ultrasound
url https://www.bjbms.org/ojs/index.php/bjbms/article/view/3275
work_keys_str_mv AT enverzerem modifiedpairtechniquefortreatmentofhydatidcystsinthespleen
AT amirnuhanovic modifiedpairtechniquefortreatmentofhydatidcystsinthespleen
AT jasmincaluk modifiedpairtechniquefortreatmentofhydatidcystsinthespleen